Abstract
Clinical features were studied in patients with systemic sclerosis (SSc) who had both pulmonary fibrosis and anti-DNA topoisomerase I antibodies, and who ultimately died of this organ involvement. The subjects consisted of 62 patients with SSc. Medical records were retrospectively reviewed. The frequency of polyarthralgia was significantly higher in these patients than in other SSc patients. However, the frequency of positive reaction of rheumatoid factor was not significantly different. These results suggested that polyarthralgia as fibrotic change in the skin and contracture shows a poor prognosis in these SSc patients.
| Original language | English |
|---|---|
| Pages (from-to) | 317-318 |
| Number of pages | 2 |
| Journal | Connective Tissue |
| Volume | 26 |
| Issue number | 4 |
| Publication status | Published - 1994 |
| Externally published | Yes |
Fingerprint
Keywords
- anti-DNA topoisomerase I antibodies
- polyarthralgia
- pulmonary fibrosis
- systemic sclerosis
ASJC Scopus subject areas
- Rheumatology
Cite this
Polyarthralgia suggests poor prognosis in systemic sclerosis with both pulmonary fibrosis and anti-DNA topoisomerase I antibodies. / Kaburaki, J.; Kuwana, M.; Okano, Y.; Hirakata, Michito; Tojo, T.; Ikeda, Y.
In: Connective Tissue, Vol. 26, No. 4, 1994, p. 317-318.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Polyarthralgia suggests poor prognosis in systemic sclerosis with both pulmonary fibrosis and anti-DNA topoisomerase I antibodies
AU - Kaburaki, J.
AU - Kuwana, M.
AU - Okano, Y.
AU - Hirakata, Michito
AU - Tojo, T.
AU - Ikeda, Y.
PY - 1994
Y1 - 1994
N2 - Clinical features were studied in patients with systemic sclerosis (SSc) who had both pulmonary fibrosis and anti-DNA topoisomerase I antibodies, and who ultimately died of this organ involvement. The subjects consisted of 62 patients with SSc. Medical records were retrospectively reviewed. The frequency of polyarthralgia was significantly higher in these patients than in other SSc patients. However, the frequency of positive reaction of rheumatoid factor was not significantly different. These results suggested that polyarthralgia as fibrotic change in the skin and contracture shows a poor prognosis in these SSc patients.
AB - Clinical features were studied in patients with systemic sclerosis (SSc) who had both pulmonary fibrosis and anti-DNA topoisomerase I antibodies, and who ultimately died of this organ involvement. The subjects consisted of 62 patients with SSc. Medical records were retrospectively reviewed. The frequency of polyarthralgia was significantly higher in these patients than in other SSc patients. However, the frequency of positive reaction of rheumatoid factor was not significantly different. These results suggested that polyarthralgia as fibrotic change in the skin and contracture shows a poor prognosis in these SSc patients.
KW - anti-DNA topoisomerase I antibodies
KW - polyarthralgia
KW - pulmonary fibrosis
KW - systemic sclerosis
UR - http://www.scopus.com/inward/record.url?scp=0028673188&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028673188&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0028673188
VL - 26
SP - 317
EP - 318
JO - Connective Tissue
JF - Connective Tissue
SN - 0916-572X
IS - 4
ER -