Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus

H. Nakashima; M. Akahoshi; Y. Tanaka; K. Yamaoka; E. Ogami; S. Nagano; Y. Arinobu; H. Niiro; T. Otsuka; Y. Niho

doi:10.1093/rheumatology/38.11.1142

Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus

H. Nakashima, M. Akahoshi, Y. Tanaka, K. Yamaoka, E. Ogami, S. Nagano, Y. Arinobu, H. Niiro, T. Otsuka, Y. Niho

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Objective. To assess the association between polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) and systemic erythematosus (SLE) in Japanese people. Method. We examined the IL-10 receptor genotype of 109 SLE patients and 102 healthy subjects by the reverse transcription-polymerase chain reaction-restriction fragment length polymorphism (RT-PCR-RFLP) method. Results. There was no difference in the IL10R genotype frequencies of these two groups. Conclusion. The IL10R genotype does not determine susceptibility to SLE in Japanese people.

Original language	English
Pages (from-to)	1142-1144
Number of pages	3
Journal	Rheumatology
Volume	38
Issue number	11
DOIs	https://doi.org/10.1093/rheumatology/38.11.1142
Publication status	Published - 1999 Nov
Externally published	Yes

Keywords

IL-10
IL-10 receptor gene (IL10R)
Polymorphism
Susceptibility
Systemic lupus erythematosus

ASJC Scopus subject areas

Rheumatology
Pharmacology (medical)

Access to Document

10.1093/rheumatology/38.11.1142

Cite this

@article{025d3a9d07a6473bbbdf2942e24489cf,

title = "Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus",

abstract = "Objective. To assess the association between polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) and systemic erythematosus (SLE) in Japanese people. Method. We examined the IL-10 receptor genotype of 109 SLE patients and 102 healthy subjects by the reverse transcription-polymerase chain reaction-restriction fragment length polymorphism (RT-PCR-RFLP) method. Results. There was no difference in the IL10R genotype frequencies of these two groups. Conclusion. The IL10R genotype does not determine susceptibility to SLE in Japanese people.",

keywords = "IL-10, IL-10 receptor gene (IL10R), Polymorphism, Susceptibility, Systemic lupus erythematosus",

author = "H. Nakashima and M. Akahoshi and Y. Tanaka and K. Yamaoka and E. Ogami and S. Nagano and Y. Arinobu and H. Niiro and T. Otsuka and Y. Niho",

year = "1999",

month = nov,

doi = "10.1093/rheumatology/38.11.1142",

language = "English",

volume = "38",

pages = "1142--1144",

journal = "Rheumatology and Rehabilitation",

issn = "1462-0324",

publisher = "Oxford University Press",

number = "11",

}

TY - JOUR

T1 - Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus

AU - Nakashima, H.

AU - Akahoshi, M.

AU - Tanaka, Y.

AU - Yamaoka, K.

AU - Ogami, E.

AU - Nagano, S.

AU - Arinobu, Y.

AU - Niiro, H.

AU - Otsuka, T.

AU - Niho, Y.

PY - 1999/11

Y1 - 1999/11

N2 - Objective. To assess the association between polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) and systemic erythematosus (SLE) in Japanese people. Method. We examined the IL-10 receptor genotype of 109 SLE patients and 102 healthy subjects by the reverse transcription-polymerase chain reaction-restriction fragment length polymorphism (RT-PCR-RFLP) method. Results. There was no difference in the IL10R genotype frequencies of these two groups. Conclusion. The IL10R genotype does not determine susceptibility to SLE in Japanese people.

AB - Objective. To assess the association between polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) and systemic erythematosus (SLE) in Japanese people. Method. We examined the IL-10 receptor genotype of 109 SLE patients and 102 healthy subjects by the reverse transcription-polymerase chain reaction-restriction fragment length polymorphism (RT-PCR-RFLP) method. Results. There was no difference in the IL10R genotype frequencies of these two groups. Conclusion. The IL10R genotype does not determine susceptibility to SLE in Japanese people.

KW - IL-10

KW - IL-10 receptor gene (IL10R)

KW - Polymorphism

KW - Susceptibility

KW - Systemic lupus erythematosus

UR - http://www.scopus.com/inward/record.url?scp=6544245087&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=6544245087&partnerID=8YFLogxK

U2 - 10.1093/rheumatology/38.11.1142

DO - 10.1093/rheumatology/38.11.1142

M3 - Article

C2 - 10556270

AN - SCOPUS:6544245087

SN - 1462-0324

VL - 38

SP - 1142

EP - 1144

JO - Rheumatology and Rehabilitation

JF - Rheumatology and Rehabilitation

IS - 11

ER -

Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this