Poly(vinyl alcohol)-coated capillaries - A solution for many application areas in capillary electrophoresis

U. Jegle, R. Grimm, H. Godel, R. Schuster, G. Ross, Tomoyoshi Soga

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Poly(vinyl alcohol) (PVA)-coated capillaries can be used in many different application areas in which electroosmotic flow (EOF) suppression and avoidance of solute adsorption are prerequisites for high-efficiency separations. The chemical and surface properties of PVA capillaries are described in detail. Separations of proteins and glycoproteins using capillary zone electrophoresis (CZE) and isoelectric focusing (IEF) are also discussed, as are the separations of strongly basic substances, amines and drugs on PVA capillaries. Poly(vinyl alcohol) capillaries are suitable for the analysis of chiral substances using chargeable cyclodextrins and because of the absence of EOF they can be used in the separations of small inorganic ions and organic acids.

Original languageEnglish
Pages (from-to)176-188
Number of pages13
JournalLC GC Europe
Volume10
Issue number3
Publication statusPublished - 1997
Externally publishedYes

Fingerprint

Capillary electrophoresis
Alcohols
Organic acids
Cyclodextrins
Electrophoresis
Chemical properties
Amines
Surface properties
Glycoproteins
Ions
Adsorption
Pharmaceutical Preparations
Proteins

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Poly(vinyl alcohol)-coated capillaries - A solution for many application areas in capillary electrophoresis. / Jegle, U.; Grimm, R.; Godel, H.; Schuster, R.; Ross, G.; Soga, Tomoyoshi.

In: LC GC Europe, Vol. 10, No. 3, 1997, p. 176-188.

Research output: Contribution to journalArticle

Jegle, U, Grimm, R, Godel, H, Schuster, R, Ross, G & Soga, T 1997, 'Poly(vinyl alcohol)-coated capillaries - A solution for many application areas in capillary electrophoresis', LC GC Europe, vol. 10, no. 3, pp. 176-188.
Jegle, U. ; Grimm, R. ; Godel, H. ; Schuster, R. ; Ross, G. ; Soga, Tomoyoshi. / Poly(vinyl alcohol)-coated capillaries - A solution for many application areas in capillary electrophoresis. In: LC GC Europe. 1997 ; Vol. 10, No. 3. pp. 176-188.
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