Population attributable numbers and fractions of deaths due to smoking: A pooled analysis of 180,000 Japanese

Yoshitaka Murakami, Katsuyuki Miura, Tomonori Okamura, Hirotsugu Ueshima

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

Objective: Age- and sex-specific population attributable fraction (PAF) and premature deaths attributable to smoking were estimated from a pooled analysis of cohort studies in Japan. Methods: A pooled analysis of individual participant data from 13 well-qualified cohort studies throughout Japan (a total of 183,251 Japanese aged 40-89, 69,502 men and 113,749 women; the baseline years between 1987 and 1995 with average 10 years of follow-up) was performed. Poison regression model was used to estimate age- and sex-specific hazard ratios, and their PAFs of all-cause deaths and number of annual premature deaths attributable to smoking were estimated. Results: Overall PAF attributable to smoking was 24.6% in men and 6.0% in women. The estimated number of annual premature deaths due to smoking was 121,854 (men: 109,998; women: 11,856) in Japan. The age-specific PAF was largest in men aged 60-69 (47.7%) and in women aged 50-59 (12.2%). In the older group aged 70-79 and 80-89, PAF was 15.4% and 8.0% in men and 3.5% and 1.5% in women, respectively. Conclusions: Age-specific PAFs attributable to smoking in Japanese men are much larger than that reported from other Asian countries.

Original languageEnglish
Pages (from-to)60-65
Number of pages6
JournalPreventive Medicine
Volume52
Issue number1
DOIs
Publication statusPublished - 2011 Jan 1

Keywords

  • Pooled analysis
  • Population attributable fraction
  • Smoking
  • Total mortality

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health

Fingerprint Dive into the research topics of 'Population attributable numbers and fractions of deaths due to smoking: A pooled analysis of 180,000 Japanese'. Together they form a unique fingerprint.

Cite this