Abstract
In cervical cancer screening, several trials have shown that human papillomavirus (HPV) testing or combined HPV testing and cytology leads to earlier detection of cervical intraepithelial neoplasia Grade 3 or worse (CIN3+) compared with cytology alone. However, the availability of similar evidence in our country remains limited. In 2013, 34 local governments were selected to administer a cervical cancer screening program utilizing either cytology alone or in combination with HPV testing. We planned a cohort study to assess the effectiveness of HPV testing as a modality for cervical cancer screening. The primary outcome of this study was the incidence of CIN3+ in each group, as well as to assess the risks and benefits of receiving screening for women in both groups. These results will contribute to elucidating the details of the positive and negative impacts of introducing HPV testing into a population-based cervical cancer screening program in Japan.
| Original language | English |
|---|---|
| Pages (from-to) | 495-498 |
| Number of pages | 4 |
| Journal | Japanese Journal of Clinical Oncology |
| Volume | 48 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2018 May 1 |
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Keywords
- Cervical cancer
- Cytology
- HPV testing
- Screening
ASJC Scopus subject areas
- Oncology
- Radiology Nuclear Medicine and imaging
- Cancer Research
Cite this
Population-based cohort study assessing the efficacy of cervical cytology (Pap smear) and human papillomavirus (HPV) testing as modalities for cervical cancer screening. / Morisada, Toru; Saika, Kumiko; Saito, Eiko; Kono, Kanako; Saito, Hiroshi; Aoki, Daisuke.
In: Japanese Journal of Clinical Oncology, Vol. 48, No. 5, 01.05.2018, p. 495-498.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Population-based cohort study assessing the efficacy of cervical cytology (Pap smear) and human papillomavirus (HPV) testing as modalities for cervical cancer screening
AU - Morisada, Toru
AU - Saika, Kumiko
AU - Saito, Eiko
AU - Kono, Kanako
AU - Saito, Hiroshi
AU - Aoki, Daisuke
PY - 2018/5/1
Y1 - 2018/5/1
N2 - In cervical cancer screening, several trials have shown that human papillomavirus (HPV) testing or combined HPV testing and cytology leads to earlier detection of cervical intraepithelial neoplasia Grade 3 or worse (CIN3+) compared with cytology alone. However, the availability of similar evidence in our country remains limited. In 2013, 34 local governments were selected to administer a cervical cancer screening program utilizing either cytology alone or in combination with HPV testing. We planned a cohort study to assess the effectiveness of HPV testing as a modality for cervical cancer screening. The primary outcome of this study was the incidence of CIN3+ in each group, as well as to assess the risks and benefits of receiving screening for women in both groups. These results will contribute to elucidating the details of the positive and negative impacts of introducing HPV testing into a population-based cervical cancer screening program in Japan.
AB - In cervical cancer screening, several trials have shown that human papillomavirus (HPV) testing or combined HPV testing and cytology leads to earlier detection of cervical intraepithelial neoplasia Grade 3 or worse (CIN3+) compared with cytology alone. However, the availability of similar evidence in our country remains limited. In 2013, 34 local governments were selected to administer a cervical cancer screening program utilizing either cytology alone or in combination with HPV testing. We planned a cohort study to assess the effectiveness of HPV testing as a modality for cervical cancer screening. The primary outcome of this study was the incidence of CIN3+ in each group, as well as to assess the risks and benefits of receiving screening for women in both groups. These results will contribute to elucidating the details of the positive and negative impacts of introducing HPV testing into a population-based cervical cancer screening program in Japan.
KW - Cervical cancer
KW - Cytology
KW - HPV testing
KW - Screening
UR - http://www.scopus.com/inward/record.url?scp=85047900297&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85047900297&partnerID=8YFLogxK
U2 - 10.1093/jjco/hyy025
DO - 10.1093/jjco/hyy025
M3 - Article
C2 - 30535331
AN - SCOPUS:85047900297
VL - 48
SP - 495
EP - 498
JO - Japanese Journal of Clinical Oncology
JF - Japanese Journal of Clinical Oncology
SN - 0368-2811
IS - 5
ER -