TY - JOUR
T1 - Portable rehabilitation system with brain-computer interface for inpatients with acute and subacute stroke
T2 - A feasibility study
AU - Hashimoto, Yasunari
AU - Kakui, Toshiyuki
AU - Ushiba, Junichi
AU - Liu, Meigen
AU - Kamada, Kyousuke
AU - Ota, Tetsuo
N1 - Funding Information:
This work was supported by JSPS KAKENHI (grant numbers 16H05434 and 24500568). Our basic idea related to EEG modulation in patients with early stroke was supported by MEXT KAKENHI (grant number 15H01657). The development of the theoretical background of our BCI design was aided by JSPS KAKENHI (grant number 16K01469). We wish to thank the rehabilitation team in Asahikawa Medical University Hospital, Hokkaido, Japan, for their support in patients’ recruitment.
Publisher Copyright:
© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.
PY - 2022
Y1 - 2022
N2 - The feasibility and safety of brain-computer interface (BCI) systems for patients with acute/subacute stroke have not been established. The aim of this study was to firstly demonstrate the feasibility and safety of a bedside BCI system for inpatients with acute/subacute stroke in a small cohort of inpatients. Four inpatients with early-phase hemiplegic stroke (7–24 days from stroke onset) participated in this study. The portable BCI system showed real-time feedback of sensorimotor rhythms extracted from scalp electroencephalograms (EEGs). Patients attempted to extend the wrist on their affected side, and neuromuscular electrical stimulation was applied only when the system detected significant movement intention-related changes in EEG. Between 120 and 200 training trials per patient were successfully and safely conducted at the bedside over 2–4 days. Our results clearly indicate that the proposed bedside BCI system is feasible and safe. Larger clinical studies are needed to determine the clinical efficacy of the system and its effect size in the population of patients with acute/subacute post-stroke hemiplegia.
AB - The feasibility and safety of brain-computer interface (BCI) systems for patients with acute/subacute stroke have not been established. The aim of this study was to firstly demonstrate the feasibility and safety of a bedside BCI system for inpatients with acute/subacute stroke in a small cohort of inpatients. Four inpatients with early-phase hemiplegic stroke (7–24 days from stroke onset) participated in this study. The portable BCI system showed real-time feedback of sensorimotor rhythms extracted from scalp electroencephalograms (EEGs). Patients attempted to extend the wrist on their affected side, and neuromuscular electrical stimulation was applied only when the system detected significant movement intention-related changes in EEG. Between 120 and 200 training trials per patient were successfully and safely conducted at the bedside over 2–4 days. Our results clearly indicate that the proposed bedside BCI system is feasible and safe. Larger clinical studies are needed to determine the clinical efficacy of the system and its effect size in the population of patients with acute/subacute post-stroke hemiplegia.
KW - brain-computer interface
KW - electroencephalogram
KW - neuromuscular electrical stimulation
KW - sensorimotor rhythms
KW - stroke
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U2 - 10.1080/10400435.2020.1836067
DO - 10.1080/10400435.2020.1836067
M3 - Article
C2 - 33085573
AN - SCOPUS:85098704253
VL - 34
SP - 402
EP - 410
JO - Assistive Technology
JF - Assistive Technology
SN - 1040-0435
IS - 4
ER -