Positron emission tomography and breast lesions: Low FDG activity in early phase imaging is not essentially benign

Ashraf Anas Zytoon, Koji Murakami, Mohamed Ramdan El-Kholy, Osama Ebied

Research output: Contribution to journalArticle

4 Citations (Scopus)


The frequency of malignancy with low FDG uptake is significant and often presents diagnostic challenges. The usefulness of dual-time point FDG-PET/CT imaging (including early "after 45 minutes" and delayed "after 100 minutes," phases after radionuclide administration) for detection of such tumors has been documented. The authors present 2 cases of pathologically proven breast cancer with minimally increased FDG uptake on the initial scan (maximum standardized uptake value; SUVmax <2.5). Detection was improved by performing a dynamic PET study with early and delayed scans. Patients with a poorly visualized breast lesion due to minimal FDG uptake on the initial FDG-PET images should not be considered as benign and deserves further delayed phase imaging.

Original languageEnglish
Pages (from-to)931-933
Number of pages3
JournalClinical nuclear medicine
Issue number12
Publication statusPublished - 2008 Dec 1



  • Breast cancer
  • Delayed imaging
  • SUV
  • Standardized uptake value

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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