Positron emission tomography and breast lesions: Low FDG activity in early phase imaging is not essentially benign

Ashraf Anas Zytoon; Koji Murakami; Mohamed Ramdan El-Kholy; Osama Ebied

doi:10.1097/RLU.0b013e31818c4df6

Positron emission tomography and breast lesions: Low FDG activity in early phase imaging is not essentially benign

Ashraf Anas Zytoon, Koji Murakami, Mohamed Ramdan El-Kholy, Osama Ebied

Department of Radiology

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The frequency of malignancy with low FDG uptake is significant and often presents diagnostic challenges. The usefulness of dual-time point FDG-PET/CT imaging (including early "after 45 minutes" and delayed "after 100 minutes," phases after radionuclide administration) for detection of such tumors has been documented. The authors present 2 cases of pathologically proven breast cancer with minimally increased FDG uptake on the initial scan (maximum standardized uptake value; SUVmax <2.5). Detection was improved by performing a dynamic PET study with early and delayed scans. Patients with a poorly visualized breast lesion due to minimal FDG uptake on the initial FDG-PET images should not be considered as benign and deserves further delayed phase imaging.

Original language	English
Pages (from-to)	931-933
Number of pages	3
Journal	Clinical nuclear medicine
Volume	33
Issue number	12
DOIs	https://doi.org/10.1097/RLU.0b013e31818c4df6
Publication status	Published - 2008 Dec 1

Keywords

Breast cancer
Delayed imaging
FDG-PET/CT
SUV
Standardized uptake value

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1097/RLU.0b013e31818c4df6

Cite this

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AU - Zytoon, Ashraf Anas

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AU - El-Kholy, Mohamed Ramdan

AU - Ebied, Osama

PY - 2008/12/1

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N2 - The frequency of malignancy with low FDG uptake is significant and often presents diagnostic challenges. The usefulness of dual-time point FDG-PET/CT imaging (including early "after 45 minutes" and delayed "after 100 minutes," phases after radionuclide administration) for detection of such tumors has been documented. The authors present 2 cases of pathologically proven breast cancer with minimally increased FDG uptake on the initial scan (maximum standardized uptake value; SUVmax <2.5). Detection was improved by performing a dynamic PET study with early and delayed scans. Patients with a poorly visualized breast lesion due to minimal FDG uptake on the initial FDG-PET images should not be considered as benign and deserves further delayed phase imaging.

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KW - Delayed imaging

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KW - Standardized uptake value

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Positron emission tomography and breast lesions: Low FDG activity in early phase imaging is not essentially benign

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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