Positron emission tomography and breast lesions: Low FDG activity in early phase imaging is not essentially benign

Ashraf Anas Zytoon; Koji Murakami; Mohamed Ramdan El-Kholy; Osama Ebied

doi:10.1097/RLU.0b013e31818c4df6

Positron emission tomography and breast lesions: Low FDG activity in early phase imaging is not essentially benign

Ashraf Anas Zytoon, Koji Murakami, Mohamed Ramdan El-Kholy, Osama Ebied

Department of Radiology

Research output: Contribution to journal › Article

4 Citations (Scopus)

Abstract

The frequency of malignancy with low FDG uptake is significant and often presents diagnostic challenges. The usefulness of dual-time point FDG-PET/CT imaging (including early "after 45 minutes" and delayed "after 100 minutes," phases after radionuclide administration) for detection of such tumors has been documented. The authors present 2 cases of pathologically proven breast cancer with minimally increased FDG uptake on the initial scan (maximum standardized uptake value; SUVmax <2.5). Detection was improved by performing a dynamic PET study with early and delayed scans. Patients with a poorly visualized breast lesion due to minimal FDG uptake on the initial FDG-PET images should not be considered as benign and deserves further delayed phase imaging.

Original language	English
Pages (from-to)	931-933
Number of pages	3
Journal	Clinical nuclear medicine
Volume	33
Issue number	12
DOIs	https://doi.org/10.1097/RLU.0b013e31818c4df6
Publication status	Published - 2008 Dec 1

Keywords

Breast cancer
Delayed imaging
FDG-PET/CT
SUV
Standardized uptake value

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1097/RLU.0b013e31818c4df6

Fingerprint Dive into the research topics of 'Positron emission tomography and breast lesions: Low FDG activity in early phase imaging is not essentially benign'. Together they form a unique fingerprint.

Cite this

Zytoon, A. A., Murakami, K., El-Kholy, M. R., & Ebied, O. (2008). Positron emission tomography and breast lesions: Low FDG activity in early phase imaging is not essentially benign. Clinical nuclear medicine, 33(12), 931-933. https://doi.org/10.1097/RLU.0b013e31818c4df6

@article{bc94fce008954ca188bd1cb77d553f8f,

title = "Positron emission tomography and breast lesions: Low FDG activity in early phase imaging is not essentially benign",

abstract = "The frequency of malignancy with low FDG uptake is significant and often presents diagnostic challenges. The usefulness of dual-time point FDG-PET/CT imaging (including early {"}after 45 minutes{"} and delayed {"}after 100 minutes,{"} phases after radionuclide administration) for detection of such tumors has been documented. The authors present 2 cases of pathologically proven breast cancer with minimally increased FDG uptake on the initial scan (maximum standardized uptake value; SUVmax <2.5). Detection was improved by performing a dynamic PET study with early and delayed scans. Patients with a poorly visualized breast lesion due to minimal FDG uptake on the initial FDG-PET images should not be considered as benign and deserves further delayed phase imaging.",

keywords = "Breast cancer, Delayed imaging, FDG-PET/CT, SUV, Standardized uptake value",

author = "Zytoon, {Ashraf Anas} and Koji Murakami and El-Kholy, {Mohamed Ramdan} and Osama Ebied",

year = "2008",

month = dec,

day = "1",

doi = "10.1097/RLU.0b013e31818c4df6",

language = "English",

volume = "33",

pages = "931--933",

journal = "Clinical Nuclear Medicine",

issn = "0363-9762",

publisher = "Lippincott Williams and Wilkins",

number = "12",

}

TY - JOUR

T1 - Positron emission tomography and breast lesions

T2 - Low FDG activity in early phase imaging is not essentially benign

AU - Zytoon, Ashraf Anas

AU - Murakami, Koji

AU - El-Kholy, Mohamed Ramdan

AU - Ebied, Osama

PY - 2008/12/1

Y1 - 2008/12/1

N2 - The frequency of malignancy with low FDG uptake is significant and often presents diagnostic challenges. The usefulness of dual-time point FDG-PET/CT imaging (including early "after 45 minutes" and delayed "after 100 minutes," phases after radionuclide administration) for detection of such tumors has been documented. The authors present 2 cases of pathologically proven breast cancer with minimally increased FDG uptake on the initial scan (maximum standardized uptake value; SUVmax <2.5). Detection was improved by performing a dynamic PET study with early and delayed scans. Patients with a poorly visualized breast lesion due to minimal FDG uptake on the initial FDG-PET images should not be considered as benign and deserves further delayed phase imaging.

AB - The frequency of malignancy with low FDG uptake is significant and often presents diagnostic challenges. The usefulness of dual-time point FDG-PET/CT imaging (including early "after 45 minutes" and delayed "after 100 minutes," phases after radionuclide administration) for detection of such tumors has been documented. The authors present 2 cases of pathologically proven breast cancer with minimally increased FDG uptake on the initial scan (maximum standardized uptake value; SUVmax <2.5). Detection was improved by performing a dynamic PET study with early and delayed scans. Patients with a poorly visualized breast lesion due to minimal FDG uptake on the initial FDG-PET images should not be considered as benign and deserves further delayed phase imaging.

KW - Breast cancer

KW - Delayed imaging

KW - FDG-PET/CT

KW - SUV

KW - Standardized uptake value

UR - http://www.scopus.com/inward/record.url?scp=58749105154&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58749105154&partnerID=8YFLogxK

U2 - 10.1097/RLU.0b013e31818c4df6

DO - 10.1097/RLU.0b013e31818c4df6

M3 - Article

C2 - 19033814

AN - SCOPUS:58749105154

VL - 33

SP - 931

EP - 933

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

SN - 0363-9762

IS - 12

ER -