Possible clinical significance of serum soluble interleukin-2 receptor level in primary bone lymphoma: Two case reports

Hiroki Yabe, Hironori Ueno, Kensuke Ochi, Hideo Morioka, Hiroo Yabe, Chihiro Terai

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2 Citations (Scopus)


In two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course. In both cases, sIL-2R levels were high before treatment and normalized with the therapeutic effects of chemotherapy, coinciding with the changes in lactate dehydrogenase levels and radiographic findings. Adding to the recently reported results of the diagnostic ability of sIL-2R in PBL, our case study highlights the clinical significance of serum sIL-2R levels as a tumor marker in PBL cases.

Original languageEnglish
Pages (from-to)125-131
Number of pages7
JournalCase Reports in Oncology
Issue number1
Publication statusPublished - 2011 Jan



  • PBL
  • Primary bone lymphoma
  • sIL-2R
  • Soluble interleukin-2 receptor
  • Tumor marker

ASJC Scopus subject areas

  • Oncology

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