Possible clinical significance of serum soluble interleukin-2 receptor level in primary bone lymphoma: Two case reports

Hiroki Yabe; Hironori Ueno; Kensuke Ochi; Hideo Morioka; Hiroo Yabe; Chihiro Terai

doi:10.1159/000325399

Possible clinical significance of serum soluble interleukin-2 receptor level in primary bone lymphoma: Two case reports

Hiroki Yabe, Hironori Ueno, Kensuke Ochi, Hideo Morioka, Hiroo Yabe, Chihiro Terai

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

In two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course. In both cases, sIL-2R levels were high before treatment and normalized with the therapeutic effects of chemotherapy, coinciding with the changes in lactate dehydrogenase levels and radiographic findings. Adding to the recently reported results of the diagnostic ability of sIL-2R in PBL, our case study highlights the clinical significance of serum sIL-2R levels as a tumor marker in PBL cases.

Original language	English
Pages (from-to)	125-131
Number of pages	7
Journal	Case Reports in Oncology
Volume	4
Issue number	1
DOIs	https://doi.org/10.1159/000325399
Publication status	Published - 2011 Jan
Externally published	Yes

Keywords

PBL
Primary bone lymphoma
Soluble interleukin-2 receptor
Tumor marker
sIL-2R

ASJC Scopus subject areas

Oncology

Access to Document

10.1159/000325399

Cite this

@article{c3e1a01efed54e9d8079faae934bc303,

title = "Possible clinical significance of serum soluble interleukin-2 receptor level in primary bone lymphoma: Two case reports",

abstract = "In two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course. In both cases, sIL-2R levels were high before treatment and normalized with the therapeutic effects of chemotherapy, coinciding with the changes in lactate dehydrogenase levels and radiographic findings. Adding to the recently reported results of the diagnostic ability of sIL-2R in PBL, our case study highlights the clinical significance of serum sIL-2R levels as a tumor marker in PBL cases.",

keywords = "PBL, Primary bone lymphoma, Soluble interleukin-2 receptor, Tumor marker, sIL-2R",

author = "Hiroki Yabe and Hironori Ueno and Kensuke Ochi and Hideo Morioka and Hiroo Yabe and Chihiro Terai",

year = "2011",

month = jan,

doi = "10.1159/000325399",

language = "English",

volume = "4",

pages = "125--131",

journal = "Case Reports in Oncology",

issn = "1662-6575",

publisher = "S. Karger AG",

number = "1",

}

TY - JOUR

T1 - Possible clinical significance of serum soluble interleukin-2 receptor level in primary bone lymphoma

T2 - Two case reports

AU - Yabe, Hiroki

AU - Ueno, Hironori

AU - Ochi, Kensuke

AU - Morioka, Hideo

AU - Yabe, Hiroo

AU - Terai, Chihiro

PY - 2011/1

Y1 - 2011/1

N2 - In two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course. In both cases, sIL-2R levels were high before treatment and normalized with the therapeutic effects of chemotherapy, coinciding with the changes in lactate dehydrogenase levels and radiographic findings. Adding to the recently reported results of the diagnostic ability of sIL-2R in PBL, our case study highlights the clinical significance of serum sIL-2R levels as a tumor marker in PBL cases.

AB - In two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course. In both cases, sIL-2R levels were high before treatment and normalized with the therapeutic effects of chemotherapy, coinciding with the changes in lactate dehydrogenase levels and radiographic findings. Adding to the recently reported results of the diagnostic ability of sIL-2R in PBL, our case study highlights the clinical significance of serum sIL-2R levels as a tumor marker in PBL cases.

KW - PBL

KW - Primary bone lymphoma

KW - Soluble interleukin-2 receptor

KW - Tumor marker

KW - sIL-2R

UR - http://www.scopus.com/inward/record.url?scp=79957623328&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79957623328&partnerID=8YFLogxK

U2 - 10.1159/000325399

DO - 10.1159/000325399

M3 - Article

C2 - 21475602

AN - SCOPUS:79957623328

SN - 1662-6575

VL - 4

SP - 125

EP - 131

JO - Case Reports in Oncology

JF - Case Reports in Oncology

IS - 1

ER -

Possible clinical significance of serum soluble interleukin-2 receptor level in primary bone lymphoma: Two case reports

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this