@article{0ef4f23222854afd81dfe3f97e37e8fe,
title = "Possible involvement of central atrial natriuretic polypeptide in regulation of hypothalamo-pituitary-adrenal axis in conscious rats",
abstract = "The effects of intracerebroventricular (i.c.v.) administration of angiotensin II (AII) and atrial natriuretic polypeptide (ANP) on the plasma corticosterone level were studied in conscious, unrestrained rats. Although i.c.v. injection of ANP had no apparent effect on the basal plasma corticosterone level, it attenuated the plasma corticosterone increase induced by centrally injected AII dose-dependently. These results suggest that ANP in the brain is involved in the regulation of the hypothalamo-pituitary-adrenal axis.",
keywords = "Angiotensin II, Atrial natriuretic polypeptide, Corticosterone, Hypothalamo-pituitary-adrenal axis",
author = "Hiroshi Itoh and Kazuwa Nakao and Goro Katsuura and Narito Morii and Takayuki Yamada and Shozo Shiono and Makoto Sakamoto and Akira Sugawara and Yoshihiko Saito and Masami Eigyo and Akira Matsushita and Hiroo Imura",
note = "Funding Information: We thank Mrs. Hiroko Tabata and Miss Kazuko Horii for the secretarial assistance. This work was supported in part by research grants from the Japanese Ministry of Education, Science and Culture, the Japanese Ministry of Health and Welfare 'Disorders of Adrenal Hormone{"} Research Committee, Japan, 1985, Japan Tobacco Inc. and Yamanouchi Foundation t\)r Research on Metabolic Disorders, by a research grant for cardiovascular diseases (60A-3) fi'om the Japanese Ministry of Health and Wclfare and by Japan Heart Foundation Research Grant For 1985.",
year = "1986",
month = sep,
day = "12",
doi = "10.1016/0304-3940(86)90489-1",
language = "English",
volume = "69",
pages = "254--258",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "3",
}