Postnatal delayed exacerbation of dural sinus malformation associated with brainstem cavernous malformations: A case report

Katsuhiro Mizutani, Tomoru Miwa, Takenori Akiyama, Tokunori Kanazawa, Hideaki Nagashima, Kei Miyakoshi, Yasunari Niimi, Kazunari Yoshida

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Dural sinus malformation (DSM) is a rare paediatric vascular malformation characterised by abnormal dilation of the posterior dural sinus. Owing to its rarity, the pathophysiology of DSM has not been fully elucidated. We report a case of prenatally diagnosed DSM with an unusual clinical course. We detected DSM in a male foetus in the 26th week of gestation by using foetal ultrasonography. Although the DSM regressed during the foetal stage and the arteriovenous shunt was insignificant in the neonate, the shunt rapidly developed four months after birth. The neonate also had postnatal de novo brainstem cavernous malformation (CM), which also developed rapidly, supposedly due to the aggravated venous hypertension resulting from the DSM. We successfully treated the aggravated shunts by endovascular transarterial and transvenous embolisation six times over two years and, subsequently, the clinical condition and the size of the brainstem CM became stable. The DSM and CM seemed to have a metameric origin. Such aberrant cases could help to further the understanding of DSM.

Original languageEnglish
Pages (from-to)510-515
Number of pages6
JournalInterventional Neuroradiology
Volume23
Issue number5
DOIs
Publication statusPublished - 2017 Oct 1

Fingerprint

Brain Stem
Prenatal Ultrasonography
Cavernous Sinus
Vascular Malformations
Dilatation
Fetus
Parturition
Pediatrics
Hypertension
Pregnancy

Keywords

  • cavernous malformation
  • cerebrofacial venous metameric syndrome
  • Dural sinus malformation
  • endovascular treatment
  • paediatric arteriovenous shunts

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Cite this

Postnatal delayed exacerbation of dural sinus malformation associated with brainstem cavernous malformations : A case report. / Mizutani, Katsuhiro; Miwa, Tomoru; Akiyama, Takenori; Kanazawa, Tokunori; Nagashima, Hideaki; Miyakoshi, Kei; Niimi, Yasunari; Yoshida, Kazunari.

In: Interventional Neuroradiology, Vol. 23, No. 5, 01.10.2017, p. 510-515.

Research output: Contribution to journalArticle

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