Potent antihepatotoxic activity of dicaffeoyl quinic acids from propolis

Purusotam Basnet, Katsumichi Matsushige, Kouji Hase, Shigetoshi Kadota, Tsuneo Namba

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Hepatoprotective activity guided chemical analyses led to the isolation of two dicaffeoyl quinic acid derivatives, methyl 3,4- di-O-caffeoyl quinate (1) and 3,4-di-O-caffeoyl quinic acid (2) from water extract of propolis, and their structures were determined by the use of 2D NMR. These compounds were stronger antihepatotoxic agents than glycyrrhizin.

Original languageEnglish
Pages (from-to)655-657
Number of pages3
JournalBiological and Pharmaceutical Bulletin
Volume19
Issue number4
Publication statusPublished - 1996 Apr
Externally publishedYes

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Quinic Acid
Propolis
Glycyrrhizic Acid
Water

Keywords

  • 3,4-di-O-caffeoyl quinic acid
  • hepatoprotective activity
  • liver
  • methyl 3,4-di-O-caffeoyl quinate
  • propolis

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Basnet, P., Matsushige, K., Hase, K., Kadota, S., & Namba, T. (1996). Potent antihepatotoxic activity of dicaffeoyl quinic acids from propolis. Biological and Pharmaceutical Bulletin, 19(4), 655-657.

Potent antihepatotoxic activity of dicaffeoyl quinic acids from propolis. / Basnet, Purusotam; Matsushige, Katsumichi; Hase, Kouji; Kadota, Shigetoshi; Namba, Tsuneo.

In: Biological and Pharmaceutical Bulletin, Vol. 19, No. 4, 04.1996, p. 655-657.

Research output: Contribution to journalArticle

Basnet, P, Matsushige, K, Hase, K, Kadota, S & Namba, T 1996, 'Potent antihepatotoxic activity of dicaffeoyl quinic acids from propolis', Biological and Pharmaceutical Bulletin, vol. 19, no. 4, pp. 655-657.
Basnet, Purusotam ; Matsushige, Katsumichi ; Hase, Kouji ; Kadota, Shigetoshi ; Namba, Tsuneo. / Potent antihepatotoxic activity of dicaffeoyl quinic acids from propolis. In: Biological and Pharmaceutical Bulletin. 1996 ; Vol. 19, No. 4. pp. 655-657.
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