Potential for local resection with sentinel node basin dissection for early gastric cancer based on the distribution of primary sites

Junya Aoyama, Hirofumi Kawakubo, Osamu Goto, Tadaki Nakahara, Shuhei Mayanagi, Kazumasa Fukuda, Koichi Suda, Rieko Nakamura, Norihito Wada, Hiroya Takeuchi, Yuukou Kitagawa

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2 Citations (Scopus)

Abstract

Background: Based on the sentinel node (SN) concept, function-preserving surgery with SN basin dissection (SNBD) can be performed for SN-negative early gastric cancers. Particularly, a resection area can be minimized when the SN basin and primary site are closely localized. The aim of this study was to compare probabilities of being candidates for local resection with SNBD based on tumor location among patients with early gastric cancer. Methods: We retrospectively analyzed 358 patients who underwent surgery with SN mapping for gastric cancer in our institution from November 1999 to April 2014. The proportion of patients who had a localized single basin and the distributions of the SN basins and primary sites were investigated. Patients with single basin drainage excluding remote sentinel node basin were considered as candidates for local resection with SNBD. Results: Of the 358 patients, 191 (53%) patients were considered eligible for local resection with SNBD. Patients with tumors located in the upper third of the stomach were more likely candidates for local resection than those with tumors in other locations (upper third, 68%; middle third, 50%; and lower third, 51%), whereas patients with tumors located in the anterior wall were less likely candidates than those with tumors other locations (anterior wall, 31%; posterior wall, 58%; greater curvature, 55%; and lesser curvature, 57%). Conclusion: We found that > 50% of the patients indicated for SN navigation surgery, particularly those with tumors in the upper third of the stomach, potentially could undergo partial resection with SNBD.

Original languageEnglish
JournalGastric Cancer
DOIs
Publication statusAccepted/In press - 2018 Jan 1

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Stomach Neoplasms
Dissection
Neoplasms
Stomach
cyhalothrin
Drainage

Keywords

  • Early gastric cancer
  • Local resection
  • Minimally invasive surgery
  • Sentinel node navigation surgery

ASJC Scopus subject areas

  • Oncology
  • Gastroenterology
  • Cancer Research

Cite this

@article{68789eabda1749c79fd0e6f467c401b2,
title = "Potential for local resection with sentinel node basin dissection for early gastric cancer based on the distribution of primary sites",
abstract = "Background: Based on the sentinel node (SN) concept, function-preserving surgery with SN basin dissection (SNBD) can be performed for SN-negative early gastric cancers. Particularly, a resection area can be minimized when the SN basin and primary site are closely localized. The aim of this study was to compare probabilities of being candidates for local resection with SNBD based on tumor location among patients with early gastric cancer. Methods: We retrospectively analyzed 358 patients who underwent surgery with SN mapping for gastric cancer in our institution from November 1999 to April 2014. The proportion of patients who had a localized single basin and the distributions of the SN basins and primary sites were investigated. Patients with single basin drainage excluding remote sentinel node basin were considered as candidates for local resection with SNBD. Results: Of the 358 patients, 191 (53{\%}) patients were considered eligible for local resection with SNBD. Patients with tumors located in the upper third of the stomach were more likely candidates for local resection than those with tumors in other locations (upper third, 68{\%}; middle third, 50{\%}; and lower third, 51{\%}), whereas patients with tumors located in the anterior wall were less likely candidates than those with tumors other locations (anterior wall, 31{\%}; posterior wall, 58{\%}; greater curvature, 55{\%}; and lesser curvature, 57{\%}). Conclusion: We found that > 50{\%} of the patients indicated for SN navigation surgery, particularly those with tumors in the upper third of the stomach, potentially could undergo partial resection with SNBD.",
keywords = "Early gastric cancer, Local resection, Minimally invasive surgery, Sentinel node navigation surgery",
author = "Junya Aoyama and Hirofumi Kawakubo and Osamu Goto and Tadaki Nakahara and Shuhei Mayanagi and Kazumasa Fukuda and Koichi Suda and Rieko Nakamura and Norihito Wada and Hiroya Takeuchi and Yuukou Kitagawa",
year = "2018",
month = "1",
day = "1",
doi = "10.1007/s10120-018-0865-3",
language = "English",
journal = "Gastric Cancer",
issn = "1436-3291",
publisher = "Springer Japan",

}

TY - JOUR

T1 - Potential for local resection with sentinel node basin dissection for early gastric cancer based on the distribution of primary sites

AU - Aoyama, Junya

AU - Kawakubo, Hirofumi

AU - Goto, Osamu

AU - Nakahara, Tadaki

AU - Mayanagi, Shuhei

AU - Fukuda, Kazumasa

AU - Suda, Koichi

AU - Nakamura, Rieko

AU - Wada, Norihito

AU - Takeuchi, Hiroya

AU - Kitagawa, Yuukou

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Background: Based on the sentinel node (SN) concept, function-preserving surgery with SN basin dissection (SNBD) can be performed for SN-negative early gastric cancers. Particularly, a resection area can be minimized when the SN basin and primary site are closely localized. The aim of this study was to compare probabilities of being candidates for local resection with SNBD based on tumor location among patients with early gastric cancer. Methods: We retrospectively analyzed 358 patients who underwent surgery with SN mapping for gastric cancer in our institution from November 1999 to April 2014. The proportion of patients who had a localized single basin and the distributions of the SN basins and primary sites were investigated. Patients with single basin drainage excluding remote sentinel node basin were considered as candidates for local resection with SNBD. Results: Of the 358 patients, 191 (53%) patients were considered eligible for local resection with SNBD. Patients with tumors located in the upper third of the stomach were more likely candidates for local resection than those with tumors in other locations (upper third, 68%; middle third, 50%; and lower third, 51%), whereas patients with tumors located in the anterior wall were less likely candidates than those with tumors other locations (anterior wall, 31%; posterior wall, 58%; greater curvature, 55%; and lesser curvature, 57%). Conclusion: We found that > 50% of the patients indicated for SN navigation surgery, particularly those with tumors in the upper third of the stomach, potentially could undergo partial resection with SNBD.

AB - Background: Based on the sentinel node (SN) concept, function-preserving surgery with SN basin dissection (SNBD) can be performed for SN-negative early gastric cancers. Particularly, a resection area can be minimized when the SN basin and primary site are closely localized. The aim of this study was to compare probabilities of being candidates for local resection with SNBD based on tumor location among patients with early gastric cancer. Methods: We retrospectively analyzed 358 patients who underwent surgery with SN mapping for gastric cancer in our institution from November 1999 to April 2014. The proportion of patients who had a localized single basin and the distributions of the SN basins and primary sites were investigated. Patients with single basin drainage excluding remote sentinel node basin were considered as candidates for local resection with SNBD. Results: Of the 358 patients, 191 (53%) patients were considered eligible for local resection with SNBD. Patients with tumors located in the upper third of the stomach were more likely candidates for local resection than those with tumors in other locations (upper third, 68%; middle third, 50%; and lower third, 51%), whereas patients with tumors located in the anterior wall were less likely candidates than those with tumors other locations (anterior wall, 31%; posterior wall, 58%; greater curvature, 55%; and lesser curvature, 57%). Conclusion: We found that > 50% of the patients indicated for SN navigation surgery, particularly those with tumors in the upper third of the stomach, potentially could undergo partial resection with SNBD.

KW - Early gastric cancer

KW - Local resection

KW - Minimally invasive surgery

KW - Sentinel node navigation surgery

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JO - Gastric Cancer

JF - Gastric Cancer

SN - 1436-3291

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