Preliminary study of laser welding for aortic dissection in a porcine model using a diode laser with indocyanine green

Masanori Fujita, Yuji Morimoto, Sayaka Ohmori, Noriko Usami, Tsunenori Arai, Tadaaki Maehara, Makoto Kikuchi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background and Objectives: The objective of this study was to determine whether a dissected aorta could be welded by a diode laser with a solder using an in vitro porcine aortic dissection model. Study Design/Materials and Methods: Porcine aortic strips were dissected into two flaps and the dissected faces were immersed in a solution of indocyanine green. The two flaps were pressed at 0.2 kg/cm2 with contact between the two immersed faces. The pressed flaps were irradiated with a diode laser (810 nm) at intensities of 170-425 W/cm2 for 8 seconds. The welded flaps were studied by light microscopy and the adhesive strengths were measured. Results: The irradiated flaps were successfully welded. The breaking stress, the maximum stress recorded in a stress-strain curve, increased with increase in irradiation intensity up to 396 W/cm2 (2.7 x 102 mmHg) and decreased when the intensity reached 425 W/cm2. In the specimen irradiated at 396 W/cm2, the welded faces showed continuous fusion of elastin layers, while some voids were seen between the welded faces in the specimen irradiated at 425 W/cm2. Conclusions: The dissected porcine aortas were successfully welded using a laser with solder. The results suggest that the welded aorta can bear physiological blood pressure.

Original languageEnglish
Pages (from-to)341-345
Number of pages5
JournalLasers in Surgery and Medicine
Volume32
Issue number5
DOIs
Publication statusPublished - 2003 Jul 8

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Keywords

  • Breaking stress
  • Collagen
  • Elastica-Masson's stain
  • Elastin
  • Irradiation intensity

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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