Preliminary study of laser welding for aortic dissection in a porcine model using a diode laser with indocyanine green

Masanori Fujita, Yuji Morimoto, Sayaka Ohmori, Noriko Usami, Tsunenori Arai, Tadaaki Maehara, Makoto Kikuchi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background and Objectives: The objective of this study was to determine whether a dissected aorta could be welded by a diode laser with a solder using an in vitro porcine aortic dissection model. Study Design/Materials and Methods: Porcine aortic strips were dissected into two flaps and the dissected faces were immersed in a solution of indocyanine green. The two flaps were pressed at 0.2 kg/cm2 with contact between the two immersed faces. The pressed flaps were irradiated with a diode laser (810 nm) at intensities of 170-425 W/cm2 for 8 seconds. The welded flaps were studied by light microscopy and the adhesive strengths were measured. Results: The irradiated flaps were successfully welded. The breaking stress, the maximum stress recorded in a stress-strain curve, increased with increase in irradiation intensity up to 396 W/cm2 (2.7 x 102 mmHg) and decreased when the intensity reached 425 W/cm2. In the specimen irradiated at 396 W/cm2, the welded faces showed continuous fusion of elastin layers, while some voids were seen between the welded faces in the specimen irradiated at 425 W/cm2. Conclusions: The dissected porcine aortas were successfully welded using a laser with solder. The results suggest that the welded aorta can bear physiological blood pressure.

Original languageEnglish
Pages (from-to)341-345
Number of pages5
JournalLasers in Surgery and Medicine
Volume32
Issue number5
DOIs
Publication statusPublished - 2003

Fingerprint

Welding
Semiconductor Lasers
Indocyanine Green
Aorta
Dissection
Lasers
Swine
Elastin
Adhesives
Microscopy
Blood Pressure
Light

Keywords

  • Breaking stress
  • Collagen
  • Elastica-Masson's stain
  • Elastin
  • Irradiation intensity

ASJC Scopus subject areas

  • Surgery

Cite this

Preliminary study of laser welding for aortic dissection in a porcine model using a diode laser with indocyanine green. / Fujita, Masanori; Morimoto, Yuji; Ohmori, Sayaka; Usami, Noriko; Arai, Tsunenori; Maehara, Tadaaki; Kikuchi, Makoto.

In: Lasers in Surgery and Medicine, Vol. 32, No. 5, 2003, p. 341-345.

Research output: Contribution to journalArticle

Fujita, Masanori ; Morimoto, Yuji ; Ohmori, Sayaka ; Usami, Noriko ; Arai, Tsunenori ; Maehara, Tadaaki ; Kikuchi, Makoto. / Preliminary study of laser welding for aortic dissection in a porcine model using a diode laser with indocyanine green. In: Lasers in Surgery and Medicine. 2003 ; Vol. 32, No. 5. pp. 341-345.
@article{6d0bcf1bc26f46448dbe8a2ffa8ad815,
title = "Preliminary study of laser welding for aortic dissection in a porcine model using a diode laser with indocyanine green",
abstract = "Background and Objectives: The objective of this study was to determine whether a dissected aorta could be welded by a diode laser with a solder using an in vitro porcine aortic dissection model. Study Design/Materials and Methods: Porcine aortic strips were dissected into two flaps and the dissected faces were immersed in a solution of indocyanine green. The two flaps were pressed at 0.2 kg/cm2 with contact between the two immersed faces. The pressed flaps were irradiated with a diode laser (810 nm) at intensities of 170-425 W/cm2 for 8 seconds. The welded flaps were studied by light microscopy and the adhesive strengths were measured. Results: The irradiated flaps were successfully welded. The breaking stress, the maximum stress recorded in a stress-strain curve, increased with increase in irradiation intensity up to 396 W/cm2 (2.7 x 102 mmHg) and decreased when the intensity reached 425 W/cm2. In the specimen irradiated at 396 W/cm2, the welded faces showed continuous fusion of elastin layers, while some voids were seen between the welded faces in the specimen irradiated at 425 W/cm2. Conclusions: The dissected porcine aortas were successfully welded using a laser with solder. The results suggest that the welded aorta can bear physiological blood pressure.",
keywords = "Breaking stress, Collagen, Elastica-Masson's stain, Elastin, Irradiation intensity",
author = "Masanori Fujita and Yuji Morimoto and Sayaka Ohmori and Noriko Usami and Tsunenori Arai and Tadaaki Maehara and Makoto Kikuchi",
year = "2003",
doi = "10.1002/lsm.10177",
language = "English",
volume = "32",
pages = "341--345",
journal = "Lasers in Surgery and Medicine",
issn = "0196-8092",
publisher = "Wiley-Liss Inc.",
number = "5",

}

TY - JOUR

T1 - Preliminary study of laser welding for aortic dissection in a porcine model using a diode laser with indocyanine green

AU - Fujita, Masanori

AU - Morimoto, Yuji

AU - Ohmori, Sayaka

AU - Usami, Noriko

AU - Arai, Tsunenori

AU - Maehara, Tadaaki

AU - Kikuchi, Makoto

PY - 2003

Y1 - 2003

N2 - Background and Objectives: The objective of this study was to determine whether a dissected aorta could be welded by a diode laser with a solder using an in vitro porcine aortic dissection model. Study Design/Materials and Methods: Porcine aortic strips were dissected into two flaps and the dissected faces were immersed in a solution of indocyanine green. The two flaps were pressed at 0.2 kg/cm2 with contact between the two immersed faces. The pressed flaps were irradiated with a diode laser (810 nm) at intensities of 170-425 W/cm2 for 8 seconds. The welded flaps were studied by light microscopy and the adhesive strengths were measured. Results: The irradiated flaps were successfully welded. The breaking stress, the maximum stress recorded in a stress-strain curve, increased with increase in irradiation intensity up to 396 W/cm2 (2.7 x 102 mmHg) and decreased when the intensity reached 425 W/cm2. In the specimen irradiated at 396 W/cm2, the welded faces showed continuous fusion of elastin layers, while some voids were seen between the welded faces in the specimen irradiated at 425 W/cm2. Conclusions: The dissected porcine aortas were successfully welded using a laser with solder. The results suggest that the welded aorta can bear physiological blood pressure.

AB - Background and Objectives: The objective of this study was to determine whether a dissected aorta could be welded by a diode laser with a solder using an in vitro porcine aortic dissection model. Study Design/Materials and Methods: Porcine aortic strips were dissected into two flaps and the dissected faces were immersed in a solution of indocyanine green. The two flaps were pressed at 0.2 kg/cm2 with contact between the two immersed faces. The pressed flaps were irradiated with a diode laser (810 nm) at intensities of 170-425 W/cm2 for 8 seconds. The welded flaps were studied by light microscopy and the adhesive strengths were measured. Results: The irradiated flaps were successfully welded. The breaking stress, the maximum stress recorded in a stress-strain curve, increased with increase in irradiation intensity up to 396 W/cm2 (2.7 x 102 mmHg) and decreased when the intensity reached 425 W/cm2. In the specimen irradiated at 396 W/cm2, the welded faces showed continuous fusion of elastin layers, while some voids were seen between the welded faces in the specimen irradiated at 425 W/cm2. Conclusions: The dissected porcine aortas were successfully welded using a laser with solder. The results suggest that the welded aorta can bear physiological blood pressure.

KW - Breaking stress

KW - Collagen

KW - Elastica-Masson's stain

KW - Elastin

KW - Irradiation intensity

UR - http://www.scopus.com/inward/record.url?scp=0038269337&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0038269337&partnerID=8YFLogxK

U2 - 10.1002/lsm.10177

DO - 10.1002/lsm.10177

M3 - Article

C2 - 12766955

AN - SCOPUS:0038269337

VL - 32

SP - 341

EP - 345

JO - Lasers in Surgery and Medicine

JF - Lasers in Surgery and Medicine

SN - 0196-8092

IS - 5

ER -