Premature ovarian failure and androgen receptor gene CAG repeat lengths weighted by X chromosome inactivation patterns

Fumihiro Sugawa, Yuka Wada, Tetsuo Maruyama, Hiroshi Uchida, Bunpei Ishizuka, Tsutomu Ogata

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The CAG repeat lengths weighted by X-inactivation ratios were significantly shorter in 58 Japanese patients with premature ovarian failure (POF) than in 42 age-matched control females with normal menses. The results suggest that short CAG repeats with a relatively high androgen receptor function may constitute a susceptibility factor for the development of POF.

Original languageEnglish
Pages (from-to)649-652
Number of pages4
JournalFertility and Sterility
Volume91
Issue number2
DOIs
Publication statusPublished - 2009 Feb 1

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

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