Preoperatively determining the margins of subcutaneous malignant soft tissue tumours using contrast-enhanced ultrasonography

Sota Oguro, Kazutaka Kikuta, Aya Sasaki, Kiyoshi Okuma, Shunsuke Matsumoto, Hiroaki Sugiura, Hideo Morioka, Masaya Nakamura, Morio Matsumoto, Masahiro Jinzaki

Research output: Contribution to journalArticle

Abstract

The purpose of this technical report is to demonstrate the feasibility of contrast-enhanced ultrasonography for preoperative evaluation of the lateral extent of subcutaneous malignant soft tissue tumours. Patients with subcutaneous malignant soft tissue tumours who underwent surgery between March 2016 and May 2016 were selected for inclusion. Contrast-enhanced ultrasonography using Sonazoid® was performed 1 day before the operation. The tumour margin was determined based on contrast-enhanced ultrasonography and marked on the skin using a permanent marker. After surgery, the extent of the tumour area was determined based on microscopic findings. The distance between the edge of the tumour and the skin markings was histologically measured. The mean distance between the extent of infiltrative tumour growth based on the microscopic findings and the skin marking was 1.3 ± 1.6 mm. The greatest distance between microscopically determined tumour invasion and the skin marking was 4 mm. Contrast-enhanced ultrasonography of subcutaneous malignant soft tissue tumours was not only feasible, but also highly accurate in estimating tumour margins as well as infiltrative tumour growth compared with macroscopic and microscopic analysis, respectively.

Original languageEnglish
Pages (from-to)1-4
Number of pages4
JournalJournal of Medical Ultrasonics
DOIs
Publication statusAccepted/In press - 2017 Sep 11

Fingerprint

Ultrasonography
Neoplasms
Skin
Growth

Keywords

  • Contrast-enhanced ultrasonography
  • Soft tissue neoplasms
  • Subcutaneous malignant soft tissue tumour

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Preoperatively determining the margins of subcutaneous malignant soft tissue tumours using contrast-enhanced ultrasonography. / Oguro, Sota; Kikuta, Kazutaka; Sasaki, Aya; Okuma, Kiyoshi; Matsumoto, Shunsuke; Sugiura, Hiroaki; Morioka, Hideo; Nakamura, Masaya; Matsumoto, Morio; Jinzaki, Masahiro.

In: Journal of Medical Ultrasonics, 11.09.2017, p. 1-4.

Research output: Contribution to journalArticle

@article{44fce78bf73941d7a3c767e605eae5ac,
title = "Preoperatively determining the margins of subcutaneous malignant soft tissue tumours using contrast-enhanced ultrasonography",
abstract = "The purpose of this technical report is to demonstrate the feasibility of contrast-enhanced ultrasonography for preoperative evaluation of the lateral extent of subcutaneous malignant soft tissue tumours. Patients with subcutaneous malignant soft tissue tumours who underwent surgery between March 2016 and May 2016 were selected for inclusion. Contrast-enhanced ultrasonography using Sonazoid{\circledR} was performed 1 day before the operation. The tumour margin was determined based on contrast-enhanced ultrasonography and marked on the skin using a permanent marker. After surgery, the extent of the tumour area was determined based on microscopic findings. The distance between the edge of the tumour and the skin markings was histologically measured. The mean distance between the extent of infiltrative tumour growth based on the microscopic findings and the skin marking was 1.3 ± 1.6 mm. The greatest distance between microscopically determined tumour invasion and the skin marking was 4 mm. Contrast-enhanced ultrasonography of subcutaneous malignant soft tissue tumours was not only feasible, but also highly accurate in estimating tumour margins as well as infiltrative tumour growth compared with macroscopic and microscopic analysis, respectively.",
keywords = "Contrast-enhanced ultrasonography, Soft tissue neoplasms, Subcutaneous malignant soft tissue tumour",
author = "Sota Oguro and Kazutaka Kikuta and Aya Sasaki and Kiyoshi Okuma and Shunsuke Matsumoto and Hiroaki Sugiura and Hideo Morioka and Masaya Nakamura and Morio Matsumoto and Masahiro Jinzaki",
year = "2017",
month = "9",
day = "11",
doi = "10.1007/s10396-017-0826-1",
language = "English",
pages = "1--4",
journal = "Japanese Journal of Medical Ultrasonics",
issn = "1346-4523",
publisher = "Springer Japan",

}

TY - JOUR

T1 - Preoperatively determining the margins of subcutaneous malignant soft tissue tumours using contrast-enhanced ultrasonography

AU - Oguro, Sota

AU - Kikuta, Kazutaka

AU - Sasaki, Aya

AU - Okuma, Kiyoshi

AU - Matsumoto, Shunsuke

AU - Sugiura, Hiroaki

AU - Morioka, Hideo

AU - Nakamura, Masaya

AU - Matsumoto, Morio

AU - Jinzaki, Masahiro

PY - 2017/9/11

Y1 - 2017/9/11

N2 - The purpose of this technical report is to demonstrate the feasibility of contrast-enhanced ultrasonography for preoperative evaluation of the lateral extent of subcutaneous malignant soft tissue tumours. Patients with subcutaneous malignant soft tissue tumours who underwent surgery between March 2016 and May 2016 were selected for inclusion. Contrast-enhanced ultrasonography using Sonazoid® was performed 1 day before the operation. The tumour margin was determined based on contrast-enhanced ultrasonography and marked on the skin using a permanent marker. After surgery, the extent of the tumour area was determined based on microscopic findings. The distance between the edge of the tumour and the skin markings was histologically measured. The mean distance between the extent of infiltrative tumour growth based on the microscopic findings and the skin marking was 1.3 ± 1.6 mm. The greatest distance between microscopically determined tumour invasion and the skin marking was 4 mm. Contrast-enhanced ultrasonography of subcutaneous malignant soft tissue tumours was not only feasible, but also highly accurate in estimating tumour margins as well as infiltrative tumour growth compared with macroscopic and microscopic analysis, respectively.

AB - The purpose of this technical report is to demonstrate the feasibility of contrast-enhanced ultrasonography for preoperative evaluation of the lateral extent of subcutaneous malignant soft tissue tumours. Patients with subcutaneous malignant soft tissue tumours who underwent surgery between March 2016 and May 2016 were selected for inclusion. Contrast-enhanced ultrasonography using Sonazoid® was performed 1 day before the operation. The tumour margin was determined based on contrast-enhanced ultrasonography and marked on the skin using a permanent marker. After surgery, the extent of the tumour area was determined based on microscopic findings. The distance between the edge of the tumour and the skin markings was histologically measured. The mean distance between the extent of infiltrative tumour growth based on the microscopic findings and the skin marking was 1.3 ± 1.6 mm. The greatest distance between microscopically determined tumour invasion and the skin marking was 4 mm. Contrast-enhanced ultrasonography of subcutaneous malignant soft tissue tumours was not only feasible, but also highly accurate in estimating tumour margins as well as infiltrative tumour growth compared with macroscopic and microscopic analysis, respectively.

KW - Contrast-enhanced ultrasonography

KW - Soft tissue neoplasms

KW - Subcutaneous malignant soft tissue tumour

UR - http://www.scopus.com/inward/record.url?scp=85029021114&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85029021114&partnerID=8YFLogxK

U2 - 10.1007/s10396-017-0826-1

DO - 10.1007/s10396-017-0826-1

M3 - Article

SP - 1

EP - 4

JO - Japanese Journal of Medical Ultrasonics

JF - Japanese Journal of Medical Ultrasonics

SN - 1346-4523

ER -