Preparation of enantiomerically enriched compounds using enzymes; VII. A synthesis of Japanese beetle pheromone utilizing lipase-catalyzed enantioselective lactonization

Takeshi Sugai, S. Ohsawa, H. Yamada, H. Ohta

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Abstract

The Japanese beetle pheromone, (R,Z)-(-)-5-1(1-decenyl)-2-oxotetrahydrofuran, was synthesized by means of the enzymatic enantioselective lactonization of the racemic key-intermediate methyl (RS)-4-hydroxy-5-tetradecynoate.

Original languageEnglish
Pages (from-to)1112-1116
Number of pages5
JournalSynthesis
Issue number12
Publication statusPublished - 1990

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ASJC Scopus subject areas

  • Organic Chemistry

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