TY - JOUR
T1 - Preparation of (R)-ibuprofen and related carboxylic acids using microbial oxidation of an aromatic hydrocarbon by rhodococcus sp. bpm 1613t
AU - Sugai, Takeshi
AU - Mori, Kenji
N1 - Funding Information:
Acknowledgments. We thank Dr. K. Nakajima, Fermentation Research Institute, Agency of Industrial Science and Technology, Tsukuba, for his kind gift of Rhodococcus sp. BPM 1613 and helpful discussion on our experiments. We acknowledge with thanks the helpful discussion with Professor Y. Minoda and Dr. T. Omori of this Department. Our thanks are due to Mr. H. Watanabe, for his measurement of 13C-NMR spectra, and Dr. K. Okada, for his gift of an authentic sample of ibuprofen.
PY - 1984/10
Y1 - 1984/10
N2 - (R)-2-(4'-Isobutylphenyl)propanoic acid (ibuprofen), (S’)-3-(4'-isobutylphenyl)butanoic acid and (S)-4-(4'-isobutylphenyl)pentanoic acid were obtained using microbial oxidation of (±)-l- isobutyl-4-(1'-methyloctyl)benzene by Rhodococcus sp. BPM 1613.
AB - (R)-2-(4'-Isobutylphenyl)propanoic acid (ibuprofen), (S’)-3-(4'-isobutylphenyl)butanoic acid and (S)-4-(4'-isobutylphenyl)pentanoic acid were obtained using microbial oxidation of (±)-l- isobutyl-4-(1'-methyloctyl)benzene by Rhodococcus sp. BPM 1613.
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U2 - 10.1080/00021369.1984.10866522
DO - 10.1080/00021369.1984.10866522
M3 - Article
AN - SCOPUS:0343351122
SN - 0916-8451
VL - 48
SP - 2501
EP - 2504
JO - Bioscience, Biotechnology and Biochemistry
JF - Bioscience, Biotechnology and Biochemistry
IS - 10
ER -