Preparative High-Performance Liquid Chromatography on Chemically Modified Porous Glass: Isolation of Saponins from Ginseng

Hideko Kanazawa, Yoshiko Nagata, Yoshikazu Matsushima, Masashi Tomoda

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Preparative high-performance liquid chromatography on octadecylsilyl porous glass (pore size, 550 A) with acetonitrile—water as the mobile phase was applied for the isolation of saponins from Panax ginseng. In a single run, several milligrams of pure ginsenosides were obtained from 10 g of roots of Panax ginseng. The method was simple, rapid and convenient and should be applicable to isolation of other saponins of crude drugs.

Original languageEnglish
Pages (from-to)1630-1632
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume38
Issue number6
DOIs
Publication statusPublished - 1990

Keywords

  • Panax ginseng
  • ginsenoside
  • octadecylsilyl porous glass
  • preparative high-performance liquid chromatography
  • saponin

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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