Abstract
Preparative high-performance liquid chromatography on octadecylsilyl porous glass (pore size, 550 A) with acetonitrile—water as the mobile phase was applied for the isolation of saponins from Panax ginseng. In a single run, several milligrams of pure ginsenosides were obtained from 10 g of roots of Panax ginseng. The method was simple, rapid and convenient and should be applicable to isolation of other saponins of crude drugs.
| Original language | English |
|---|---|
| Pages (from-to) | 1630-1632 |
| Number of pages | 3 |
| Journal | Chemical and Pharmaceutical Bulletin |
| Volume | 38 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1990 |
Keywords
- Panax ginseng
- ginsenoside
- octadecylsilyl porous glass
- preparative high-performance liquid chromatography
- saponin
ASJC Scopus subject areas
- Chemistry(all)
- Drug Discovery
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Cite this
Kanazawa, H., Nagata, Y., Matsushima, Y., & Tomoda, M. (1990). Preparative High-Performance Liquid Chromatography on Chemically Modified Porous Glass: Isolation of Saponins from Ginseng. Chemical and Pharmaceutical Bulletin, 38(6), 1630-1632. https://doi.org/10.1248/cpb.38.1630