Preparative High-Performance Liquid Chromatography on Chemically Modified Porous Glass: Isolation of Saponins from Ginseng

Hideko Kanazawa; Yoshiko Nagata; Yoshikazu Matsushima; Masashi Tomoda

doi:10.1248/cpb.38.1630

Preparative High-Performance Liquid Chromatography on Chemically Modified Porous Glass: Isolation of Saponins from Ginseng

Hideko Kanazawa, Yoshiko Nagata, Yoshikazu Matsushima, Masashi Tomoda

School of Pharmaceutical Sciences

Research output: Contribution to journal › Article

7 Citations (Scopus)

Abstract

Preparative high-performance liquid chromatography on octadecylsilyl porous glass (pore size, 550 A) with acetonitrile—water as the mobile phase was applied for the isolation of saponins from Panax ginseng. In a single run, several milligrams of pure ginsenosides were obtained from 10 g of roots of Panax ginseng. The method was simple, rapid and convenient and should be applicable to isolation of other saponins of crude drugs.

Original language	English
Pages (from-to)	1630-1632
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	38
Issue number	6
DOIs	https://doi.org/10.1248/cpb.38.1630
Publication status	Published - 1990 Jan 1

Fingerprint

Keywords

Panax ginseng
ginsenoside
octadecylsilyl porous glass
preparative high-performance liquid chromatography
saponin

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

Cite this

Kanazawa, H., Nagata, Y., Matsushima, Y., & Tomoda, M. (1990). Preparative High-Performance Liquid Chromatography on Chemically Modified Porous Glass: Isolation of Saponins from Ginseng. Chemical and Pharmaceutical Bulletin, 38(6), 1630-1632. https://doi.org/10.1248/cpb.38.1630

@article{b1de11131a38429bac3293840a84e117,

title = "Preparative High-Performance Liquid Chromatography on Chemically Modified Porous Glass: Isolation of Saponins from Ginseng",

abstract = "Preparative high-performance liquid chromatography on octadecylsilyl porous glass (pore size, 550 A) with acetonitrile—water as the mobile phase was applied for the isolation of saponins from Panax ginseng. In a single run, several milligrams of pure ginsenosides were obtained from 10 g of roots of Panax ginseng. The method was simple, rapid and convenient and should be applicable to isolation of other saponins of crude drugs.",

keywords = "Panax ginseng, ginsenoside, octadecylsilyl porous glass, preparative high-performance liquid chromatography, saponin",

author = "Hideko Kanazawa and Yoshiko Nagata and Yoshikazu Matsushima and Masashi Tomoda",

year = "1990",

month = jan

day = "1",

doi = "10.1248/cpb.38.1630",

language = "English",

volume = "38",

pages = "1630--1632",

journal = "Chemical and Pharmaceutical Bulletin",

issn = "0009-2363",

publisher = "Pharmaceutical Society of Japan",

number = "6",

}

TY - JOUR

T1 - Preparative High-Performance Liquid Chromatography on Chemically Modified Porous Glass

T2 - Isolation of Saponins from Ginseng

AU - Kanazawa, Hideko

AU - Nagata, Yoshiko

AU - Matsushima, Yoshikazu

AU - Tomoda, Masashi

PY - 1990/1/1

Y1 - 1990/1/1

N2 - Preparative high-performance liquid chromatography on octadecylsilyl porous glass (pore size, 550 A) with acetonitrile—water as the mobile phase was applied for the isolation of saponins from Panax ginseng. In a single run, several milligrams of pure ginsenosides were obtained from 10 g of roots of Panax ginseng. The method was simple, rapid and convenient and should be applicable to isolation of other saponins of crude drugs.

AB - Preparative high-performance liquid chromatography on octadecylsilyl porous glass (pore size, 550 A) with acetonitrile—water as the mobile phase was applied for the isolation of saponins from Panax ginseng. In a single run, several milligrams of pure ginsenosides were obtained from 10 g of roots of Panax ginseng. The method was simple, rapid and convenient and should be applicable to isolation of other saponins of crude drugs.

KW - Panax ginseng

KW - ginsenoside

KW - octadecylsilyl porous glass

KW - preparative high-performance liquid chromatography

KW - saponin

UR - http://www.scopus.com/inward/record.url?scp=0025003514&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025003514&partnerID=8YFLogxK

U2 - 10.1248/cpb.38.1630

DO - 10.1248/cpb.38.1630

M3 - Article

C2 - 2208373

AN - SCOPUS:0025003514

VL - 38

SP - 1630

EP - 1632

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

SN - 0009-2363

IS - 6

ER -

Access to Document

10.1248/cpb.38.1630