Preparative High-Performance Liquid Chromatography on Chemically Modified Porous Glass: Isolation of Saponins from Ginseng

Hideko Kanazawa; Yoshiko Nagata; Yoshikazu Matsushima; Masashi Tomoda

doi:10.1248/cpb.38.1630

Preparative High-Performance Liquid Chromatography on Chemically Modified Porous Glass: Isolation of Saponins from Ginseng

Hideko Kanazawa, Yoshiko Nagata, Yoshikazu Matsushima, Masashi Tomoda

School of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Preparative high-performance liquid chromatography on octadecylsilyl porous glass (pore size, 550 A) with acetonitrile—water as the mobile phase was applied for the isolation of saponins from Panax ginseng. In a single run, several milligrams of pure ginsenosides were obtained from 10 g of roots of Panax ginseng. The method was simple, rapid and convenient and should be applicable to isolation of other saponins of crude drugs.

Original language	English
Pages (from-to)	1630-1632
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	38
Issue number	6
DOIs	https://doi.org/10.1248/cpb.38.1630
Publication status	Published - 1990

Keywords

Panax ginseng
ginsenoside
octadecylsilyl porous glass
preparative high-performance liquid chromatography
saponin

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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10.1248/cpb.38.1630

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title = "Preparative High-Performance Liquid Chromatography on Chemically Modified Porous Glass: Isolation of Saponins from Ginseng",

abstract = "Preparative high-performance liquid chromatography on octadecylsilyl porous glass (pore size, 550 A) with acetonitrile—water as the mobile phase was applied for the isolation of saponins from Panax ginseng. In a single run, several milligrams of pure ginsenosides were obtained from 10 g of roots of Panax ginseng. The method was simple, rapid and convenient and should be applicable to isolation of other saponins of crude drugs.",

keywords = "Panax ginseng, ginsenoside, octadecylsilyl porous glass, preparative high-performance liquid chromatography, saponin",

author = "Hideko Kanazawa and Yoshiko Nagata and Yoshikazu Matsushima and Masashi Tomoda",

year = "1990",

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pages = "1630--1632",

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publisher = "Pharmaceutical Society of Japan",

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T1 - Preparative High-Performance Liquid Chromatography on Chemically Modified Porous Glass

T2 - Isolation of Saponins from Ginseng

AU - Kanazawa, Hideko

AU - Nagata, Yoshiko

AU - Matsushima, Yoshikazu

AU - Tomoda, Masashi

PY - 1990

Y1 - 1990

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AB - Preparative high-performance liquid chromatography on octadecylsilyl porous glass (pore size, 550 A) with acetonitrile—water as the mobile phase was applied for the isolation of saponins from Panax ginseng. In a single run, several milligrams of pure ginsenosides were obtained from 10 g of roots of Panax ginseng. The method was simple, rapid and convenient and should be applicable to isolation of other saponins of crude drugs.

KW - Panax ginseng

KW - ginsenoside

KW - octadecylsilyl porous glass

KW - preparative high-performance liquid chromatography

KW - saponin

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