Abstract
The effects were studied of the extracts prepared from 10- and 18-day developing chick skins on collagen synthesis and proliferation of the monolayered fibroblasts established from 10-day skin. Cell proliferation was stimulated by both 10- and 18-day skin extracts at the concentration of 3.5 μg/ml. Collagen synthesis was suppressed by the treatment of extracts prepared from both 10- and 18-day skins at the concentration of 3.5 μg/ml, to a greater extent in 18-day extract. The results indicate that skin extracts possess factors exhibiting both a stimulating effect on cell proliferation and an inhibitory effect on collagen synthesis.
Original language | English |
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Pages (from-to) | 258-260 |
Number of pages | 3 |
Journal | Journal of Dermatological Science |
Volume | 6 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1993 Dec |
Keywords
- Cell proliferation
- Collagen
- Developing skin
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Dermatology