Present status of pediatric living-donor liver transplantation in National Center for Child Health and Development

Mureo Kasahara, Seisuke Sakamoto, Takanobu Shigeta, Akinari Fukuda, Naoto Matsuno, Hideaki Tanaka, Yoshihiro Kitano, Tatsuo Kuroda

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

PURPOSE: We reviewed our initial experience of pediatric living-donor liver transplantation (LDLT) in National Center for Child Health and Development and report the results herein. SUBJECTS AND METHODS: We have done 103 cases of LDLT during November 2005 through September 2009 in National Center for Child Health and Development. Variables including indication of liver transplantation/infectious/immunological outcome were reviewed. RESULTS: The indication for liver transplantation was cholestatic liver disease in 43.76%, followed by metabolic liver disease 24.3% and acute liver failure 18.5%. The mean age of recipient was 3.6 +/- 4.2 years and body weight was 14.4 +/- 11.1kg. Immunosuppression consisted of tacrolimus and low-dose steroids. The incidence of acute cellular rejection was 33.3%. The graft and patient survival were 92.2%. CONCLUSION: Satisfactory result can be achieved on LDLT program in National Center for Child Health and Development. The follow-up period was too short to make definitive conclusion, however, long-term observation may be necessary to collect sufficient data for the establishment of the treatment modality.

Original languageEnglish
Pages (from-to)268-274
Number of pages7
JournalNippon Geka Gakkai zasshi
Volume111
Issue number4
Publication statusPublished - 2010 Jul
Externally publishedYes

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Living Donors
Child Development
Liver Transplantation
Pediatrics
Liver Diseases
Acute Liver Failure
Metabolic Diseases
Tacrolimus
Graft Survival
Immunosuppression
Steroids
Body Weight
Observation
Child Health
Incidence

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Kasahara, M., Sakamoto, S., Shigeta, T., Fukuda, A., Matsuno, N., Tanaka, H., ... Kuroda, T. (2010). Present status of pediatric living-donor liver transplantation in National Center for Child Health and Development. Nippon Geka Gakkai zasshi, 111(4), 268-274.

Present status of pediatric living-donor liver transplantation in National Center for Child Health and Development. / Kasahara, Mureo; Sakamoto, Seisuke; Shigeta, Takanobu; Fukuda, Akinari; Matsuno, Naoto; Tanaka, Hideaki; Kitano, Yoshihiro; Kuroda, Tatsuo.

In: Nippon Geka Gakkai zasshi, Vol. 111, No. 4, 07.2010, p. 268-274.

Research output: Contribution to journalArticle

Kasahara, M, Sakamoto, S, Shigeta, T, Fukuda, A, Matsuno, N, Tanaka, H, Kitano, Y & Kuroda, T 2010, 'Present status of pediatric living-donor liver transplantation in National Center for Child Health and Development', Nippon Geka Gakkai zasshi, vol. 111, no. 4, pp. 268-274.
Kasahara M, Sakamoto S, Shigeta T, Fukuda A, Matsuno N, Tanaka H et al. Present status of pediatric living-donor liver transplantation in National Center for Child Health and Development. Nippon Geka Gakkai zasshi. 2010 Jul;111(4):268-274.
Kasahara, Mureo ; Sakamoto, Seisuke ; Shigeta, Takanobu ; Fukuda, Akinari ; Matsuno, Naoto ; Tanaka, Hideaki ; Kitano, Yoshihiro ; Kuroda, Tatsuo. / Present status of pediatric living-donor liver transplantation in National Center for Child Health and Development. In: Nippon Geka Gakkai zasshi. 2010 ; Vol. 111, No. 4. pp. 268-274.
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