Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: Case report

Motoko Kawashima; Hiroshi Mochizuki; Tetsuya Kawakita; Shin Hatoh; Jun Shimazaki; Masakazu Yamada

doi:10.1186/1752-1947-1-10

Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: Case report

Motoko Kawashima, Hiroshi Mochizuki, Tetsuya Kawakita, Shin Hatoh, Jun Shimazaki, Masakazu Yamada

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Purpose: To describe the development of presumed immune-mediated stromal rejection after automated lamellar therapeutic keratoplasty (ALTK) and its reversal after initiation of intensive topical corticosteroid therapy. Methods: Observational case report. Results: Stromal edema localized inthe graft developed 42 days after ALTK for Avellino corneal dystrophy in a 65-year-old man. After one week of intensive topical corticosteroids, complete reversal of graft edema occurred, with full recovery of visual function. Conclusion: The clinical appearance and response to therapy in this case supported the diagnosis of immune-mediated stromal rejection. Ophthalmologists should be aware that stromal rejection may occur in lamellar corneal grafts.

Original language	English
Article number	10
Journal	Journal of Medical Case Reports
Volume	1
DOIs	https://doi.org/10.1186/1752-1947-1-10
Publication status	Published - 2007 Apr 1
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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abstract = "Purpose: To describe the development of presumed immune-mediated stromal rejection after automated lamellar therapeutic keratoplasty (ALTK) and its reversal after initiation of intensive topical corticosteroid therapy. Methods: Observational case report. Results: Stromal edema localized inthe graft developed 42 days after ALTK for Avellino corneal dystrophy in a 65-year-old man. After one week of intensive topical corticosteroids, complete reversal of graft edema occurred, with full recovery of visual function. Conclusion: The clinical appearance and response to therapy in this case supported the diagnosis of immune-mediated stromal rejection. Ophthalmologists should be aware that stromal rejection may occur in lamellar corneal grafts.",

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T1 - Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty

T2 - Case report

AU - Kawashima, Motoko

AU - Mochizuki, Hiroshi

AU - Kawakita, Tetsuya

AU - Hatoh, Shin

AU - Shimazaki, Jun

AU - Yamada, Masakazu

PY - 2007/4/1

Y1 - 2007/4/1

N2 - Purpose: To describe the development of presumed immune-mediated stromal rejection after automated lamellar therapeutic keratoplasty (ALTK) and its reversal after initiation of intensive topical corticosteroid therapy. Methods: Observational case report. Results: Stromal edema localized inthe graft developed 42 days after ALTK for Avellino corneal dystrophy in a 65-year-old man. After one week of intensive topical corticosteroids, complete reversal of graft edema occurred, with full recovery of visual function. Conclusion: The clinical appearance and response to therapy in this case supported the diagnosis of immune-mediated stromal rejection. Ophthalmologists should be aware that stromal rejection may occur in lamellar corneal grafts.

AB - Purpose: To describe the development of presumed immune-mediated stromal rejection after automated lamellar therapeutic keratoplasty (ALTK) and its reversal after initiation of intensive topical corticosteroid therapy. Methods: Observational case report. Results: Stromal edema localized inthe graft developed 42 days after ALTK for Avellino corneal dystrophy in a 65-year-old man. After one week of intensive topical corticosteroids, complete reversal of graft edema occurred, with full recovery of visual function. Conclusion: The clinical appearance and response to therapy in this case supported the diagnosis of immune-mediated stromal rejection. Ophthalmologists should be aware that stromal rejection may occur in lamellar corneal grafts.

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Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: Case report

Abstract

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