Preventive effect on delayed gastric emptying of preserving the infra-pyloric vein in laparoscopic pylorus-preserving gastrectomy for early gastric cancer

Sanae Kaji, Rie Makuuchi, Tomoyuki Irino, Yutaka Tanizawa, Etsuro Bando, Taiichi Kawamura, Hayato Omori, Keiichi Fujiya, Noriyuki Nishiwaki, Kenichiro Furukawa, Kenichi Nakamura, Yusuke Koseki, Yuhei Waki, Raito Asaoka, Masanori Terashima

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Pylorus-preserving gastrectomy (PPG) has the postoperative advantages of a better quality of life and less weight loss than distal gastrectomy. However, postoperative delayed gastric emptying (DGE) due to antral hypomotility can be a problem. Although preserving the infra-pyloric vein (IPV) is reported to improve congestion of the antrum and prevent DGE, the benefits of this procedure have not been confirmed. The present study aimed to clarify the preventive effect on DGE of preserving the IPV. Methods: A total of 148 patients [IPV-preserved (IPVP): 78 patients and IPV-non-preserved (IPVN): 70 patients] who underwent laparoscopic and robotic PPG (LRPPG) for early gastric cancer were enrolled in this study. The clinicopathologic characteristics and incidence of DGE were compared between the groups. The nutritional risk index (NRI) at 1, 2, and 3 years after the operation and the relapse-free survival (RFS) were also compared. Results: There were no significant differences in the clinicopathological characteristics between the two groups. DGE was observed in 15 of 148 patients (10.1%). The incidence of DGE did not differ markedly between the 2 groups (IPVP vs. IPVN; 11.5% vs. 8.6% p = 0.596). There were no significant differences in other complications between the groups either (IPVP vs. IPVN; 19.2% vs. 21.4%; p = 0.838). The NRI and 3-year RFS were not significantly different between the two groups. Conclusion: Regarding LRPPG, preserving the IPV did not help prevent DGE and resulted in no significant difference in the outcomes.

Original languageEnglish
JournalSurgical Endoscopy
DOIs
Publication statusAccepted/In press - 2019 Jan 1
Externally publishedYes

Fingerprint

Gastric Emptying
Pylorus
Gastrectomy
Stomach Neoplasms
Veins
Nutrition Assessment
Robotics
Recurrence
Survival
Incidence
Weight Loss
Quality of Life

Keywords

  • Delayed gastric emptying
  • Infra-pyloric vein
  • Laparoscopic pylorus-preserving gastrectomy
  • Retrospective study

ASJC Scopus subject areas

  • Surgery

Cite this

Preventive effect on delayed gastric emptying of preserving the infra-pyloric vein in laparoscopic pylorus-preserving gastrectomy for early gastric cancer. / Kaji, Sanae; Makuuchi, Rie; Irino, Tomoyuki; Tanizawa, Yutaka; Bando, Etsuro; Kawamura, Taiichi; Omori, Hayato; Fujiya, Keiichi; Nishiwaki, Noriyuki; Furukawa, Kenichiro; Nakamura, Kenichi; Koseki, Yusuke; Waki, Yuhei; Asaoka, Raito; Terashima, Masanori.

In: Surgical Endoscopy, 01.01.2019.

Research output: Contribution to journalArticle

Kaji, S, Makuuchi, R, Irino, T, Tanizawa, Y, Bando, E, Kawamura, T, Omori, H, Fujiya, K, Nishiwaki, N, Furukawa, K, Nakamura, K, Koseki, Y, Waki, Y, Asaoka, R & Terashima, M 2019, 'Preventive effect on delayed gastric emptying of preserving the infra-pyloric vein in laparoscopic pylorus-preserving gastrectomy for early gastric cancer', Surgical Endoscopy. https://doi.org/10.1007/s00464-019-07151-9
Kaji, Sanae ; Makuuchi, Rie ; Irino, Tomoyuki ; Tanizawa, Yutaka ; Bando, Etsuro ; Kawamura, Taiichi ; Omori, Hayato ; Fujiya, Keiichi ; Nishiwaki, Noriyuki ; Furukawa, Kenichiro ; Nakamura, Kenichi ; Koseki, Yusuke ; Waki, Yuhei ; Asaoka, Raito ; Terashima, Masanori. / Preventive effect on delayed gastric emptying of preserving the infra-pyloric vein in laparoscopic pylorus-preserving gastrectomy for early gastric cancer. In: Surgical Endoscopy. 2019.
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abstract = "Background: Pylorus-preserving gastrectomy (PPG) has the postoperative advantages of a better quality of life and less weight loss than distal gastrectomy. However, postoperative delayed gastric emptying (DGE) due to antral hypomotility can be a problem. Although preserving the infra-pyloric vein (IPV) is reported to improve congestion of the antrum and prevent DGE, the benefits of this procedure have not been confirmed. The present study aimed to clarify the preventive effect on DGE of preserving the IPV. Methods: A total of 148 patients [IPV-preserved (IPVP): 78 patients and IPV-non-preserved (IPVN): 70 patients] who underwent laparoscopic and robotic PPG (LRPPG) for early gastric cancer were enrolled in this study. The clinicopathologic characteristics and incidence of DGE were compared between the groups. The nutritional risk index (NRI) at 1, 2, and 3 years after the operation and the relapse-free survival (RFS) were also compared. Results: There were no significant differences in the clinicopathological characteristics between the two groups. DGE was observed in 15 of 148 patients (10.1{\%}). The incidence of DGE did not differ markedly between the 2 groups (IPVP vs. IPVN; 11.5{\%} vs. 8.6{\%} p = 0.596). There were no significant differences in other complications between the groups either (IPVP vs. IPVN; 19.2{\%} vs. 21.4{\%}; p = 0.838). The NRI and 3-year RFS were not significantly different between the two groups. Conclusion: Regarding LRPPG, preserving the IPV did not help prevent DGE and resulted in no significant difference in the outcomes.",
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author = "Sanae Kaji and Rie Makuuchi and Tomoyuki Irino and Yutaka Tanizawa and Etsuro Bando and Taiichi Kawamura and Hayato Omori and Keiichi Fujiya and Noriyuki Nishiwaki and Kenichiro Furukawa and Kenichi Nakamura and Yusuke Koseki and Yuhei Waki and Raito Asaoka and Masanori Terashima",
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T1 - Preventive effect on delayed gastric emptying of preserving the infra-pyloric vein in laparoscopic pylorus-preserving gastrectomy for early gastric cancer

AU - Kaji, Sanae

AU - Makuuchi, Rie

AU - Irino, Tomoyuki

AU - Tanizawa, Yutaka

AU - Bando, Etsuro

AU - Kawamura, Taiichi

AU - Omori, Hayato

AU - Fujiya, Keiichi

AU - Nishiwaki, Noriyuki

AU - Furukawa, Kenichiro

AU - Nakamura, Kenichi

AU - Koseki, Yusuke

AU - Waki, Yuhei

AU - Asaoka, Raito

AU - Terashima, Masanori

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Background: Pylorus-preserving gastrectomy (PPG) has the postoperative advantages of a better quality of life and less weight loss than distal gastrectomy. However, postoperative delayed gastric emptying (DGE) due to antral hypomotility can be a problem. Although preserving the infra-pyloric vein (IPV) is reported to improve congestion of the antrum and prevent DGE, the benefits of this procedure have not been confirmed. The present study aimed to clarify the preventive effect on DGE of preserving the IPV. Methods: A total of 148 patients [IPV-preserved (IPVP): 78 patients and IPV-non-preserved (IPVN): 70 patients] who underwent laparoscopic and robotic PPG (LRPPG) for early gastric cancer were enrolled in this study. The clinicopathologic characteristics and incidence of DGE were compared between the groups. The nutritional risk index (NRI) at 1, 2, and 3 years after the operation and the relapse-free survival (RFS) were also compared. Results: There were no significant differences in the clinicopathological characteristics between the two groups. DGE was observed in 15 of 148 patients (10.1%). The incidence of DGE did not differ markedly between the 2 groups (IPVP vs. IPVN; 11.5% vs. 8.6% p = 0.596). There were no significant differences in other complications between the groups either (IPVP vs. IPVN; 19.2% vs. 21.4%; p = 0.838). The NRI and 3-year RFS were not significantly different between the two groups. Conclusion: Regarding LRPPG, preserving the IPV did not help prevent DGE and resulted in no significant difference in the outcomes.

AB - Background: Pylorus-preserving gastrectomy (PPG) has the postoperative advantages of a better quality of life and less weight loss than distal gastrectomy. However, postoperative delayed gastric emptying (DGE) due to antral hypomotility can be a problem. Although preserving the infra-pyloric vein (IPV) is reported to improve congestion of the antrum and prevent DGE, the benefits of this procedure have not been confirmed. The present study aimed to clarify the preventive effect on DGE of preserving the IPV. Methods: A total of 148 patients [IPV-preserved (IPVP): 78 patients and IPV-non-preserved (IPVN): 70 patients] who underwent laparoscopic and robotic PPG (LRPPG) for early gastric cancer were enrolled in this study. The clinicopathologic characteristics and incidence of DGE were compared between the groups. The nutritional risk index (NRI) at 1, 2, and 3 years after the operation and the relapse-free survival (RFS) were also compared. Results: There were no significant differences in the clinicopathological characteristics between the two groups. DGE was observed in 15 of 148 patients (10.1%). The incidence of DGE did not differ markedly between the 2 groups (IPVP vs. IPVN; 11.5% vs. 8.6% p = 0.596). There were no significant differences in other complications between the groups either (IPVP vs. IPVN; 19.2% vs. 21.4%; p = 0.838). The NRI and 3-year RFS were not significantly different between the two groups. Conclusion: Regarding LRPPG, preserving the IPV did not help prevent DGE and resulted in no significant difference in the outcomes.

KW - Delayed gastric emptying

KW - Infra-pyloric vein

KW - Laparoscopic pylorus-preserving gastrectomy

KW - Retrospective study

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