Primary carcinoid tumor in a polycystic kidney

Rie Shibata, Hajime Okita, Masayuki Shimoda, Hirotaka Asakura, Masaru Murai, Michiie Sakamoto, Jun Ichi Hata

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

A case of a primary carcinoid tumor within a polycystic kidney is reported. A 51-year-old woman with autosomal dominant polycystic kidney disease (ADPKD) underwent a bilateral nephrectomy because of an infection in her polycystic kidneys. A tumor (1.5 cm in diameter) was incidentally found close to the hilum of the left kidney. Histologically, the tumor exhibited a predominantly trabecular pattern of cuboidal or columnar cells. Grimelius staining showed numerous silver-stained neurosecretory granules in most of the tumor cells; the tumor cells were also positive for chromogranin, synaptophysin, prostatic acid phosphatase (PAP) and neuron-specific enolase (NSE). The tumor was diagnosed as a primary carcinoid tumor of the kidney. Primary renal carcinoid is a very rare neoplasm, and this is the first report of such a lesion arising in a polycystic kidney.

Original languageEnglish
Pages (from-to)317-322
Number of pages6
JournalPathology International
Volume53
Issue number5
DOIs
Publication statusPublished - 2003 May 1

Fingerprint

Polycystic Kidney Diseases
Carcinoid Tumor
Neoplasms
Kidney
Chromogranins
Autosomal Dominant Polycystic Kidney
Synaptophysin
Phosphopyruvate Hydratase
Nephrectomy
Silver
Staining and Labeling
Infection

Keywords

  • Autosomal dominant polycystic kidney disease (ADPKD)
  • Carcinoid tumor

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Primary carcinoid tumor in a polycystic kidney. / Shibata, Rie; Okita, Hajime; Shimoda, Masayuki; Asakura, Hirotaka; Murai, Masaru; Sakamoto, Michiie; Hata, Jun Ichi.

In: Pathology International, Vol. 53, No. 5, 01.05.2003, p. 317-322.

Research output: Contribution to journalArticle

Shibata, Rie ; Okita, Hajime ; Shimoda, Masayuki ; Asakura, Hirotaka ; Murai, Masaru ; Sakamoto, Michiie ; Hata, Jun Ichi. / Primary carcinoid tumor in a polycystic kidney. In: Pathology International. 2003 ; Vol. 53, No. 5. pp. 317-322.
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