TY - JOUR
T1 - Primary hepatic cancers with multiple pathologic features in a patient with hepatitis C
T2 - Report of a case
AU - Oshima, Go
AU - Shinoda, Masahiro
AU - Tanabe, Minoru
AU - Masugi, Yohei
AU - Ueno, Akihisa
AU - Takano, Kiminori
AU - Kitago, Minoru
AU - Itano, Osamu
AU - Kawachi, Shigeyuki
AU - Ohara, Kentaro
AU - Oda, Masaya
AU - Tanimoto, Akihiro
AU - Sakamaoto, Michiie
AU - Kitagawa, Yuko
PY - 2012/1
Y1 - 2012/1
N2 - We report a case of multiple primary hepatic cancers exhibiting different pathologic features coexisting in a patient with chronic hepatitis C. Computed tomography showed 2 tumors in segment 8, 20 mm (S8-A) and 5 mm (S8-B) in diameter, and a 10-mm tumor in segment 6 (S6). Based on the images, the S8-A lesion was diagnosed as cholangiocellular carcinoma or combined hepatocellular carcinoma and cholangiocarcinoma (combined HCC-CC). The other 2 tumors were diagnosed as HCC. The patient underwent partial resections of segments 6 and 8. We found 2 more tumors (S8-C was 6 mm in diameter and S8-D was 4 mm) in the resected segment 8 specimen. Histopathologic examination revealed that the S8-A and S8-C tumors were combined HCC-CC, the S8-B and S6 lesions were scirrhous HCC, and the S8-D tumor was an early HCC. This is a very rare case in which different hepatic cancers with multiple pathologic features coexisted.
AB - We report a case of multiple primary hepatic cancers exhibiting different pathologic features coexisting in a patient with chronic hepatitis C. Computed tomography showed 2 tumors in segment 8, 20 mm (S8-A) and 5 mm (S8-B) in diameter, and a 10-mm tumor in segment 6 (S6). Based on the images, the S8-A lesion was diagnosed as cholangiocellular carcinoma or combined hepatocellular carcinoma and cholangiocarcinoma (combined HCC-CC). The other 2 tumors were diagnosed as HCC. The patient underwent partial resections of segments 6 and 8. We found 2 more tumors (S8-C was 6 mm in diameter and S8-D was 4 mm) in the resected segment 8 specimen. Histopathologic examination revealed that the S8-A and S8-C tumors were combined HCC-CC, the S8-B and S6 lesions were scirrhous HCC, and the S8-D tumor was an early HCC. This is a very rare case in which different hepatic cancers with multiple pathologic features coexisted.
KW - Chronic hepatitis
KW - Combined hepatocellular carcinoma and cholangiocarcinoma
KW - Early hepatocellular carcinoma
KW - Hepatitis C virus
KW - Multicentric hepatocellular carcinoma
KW - Multiple pathologic features
KW - Scirrhous type of hepatocellular carcinoma
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U2 - 10.9738/CC72.1
DO - 10.9738/CC72.1
M3 - Article
C2 - 23101996
AN - SCOPUS:84871211017
SN - 0020-8868
VL - 97
SP - 17
EP - 22
JO - International Surgery
JF - International Surgery
IS - 1
ER -
