Primary invasive micropapillary carcinoma of the stomach

Masayuki Shimoda, Yasunori Okada, Yuichiro Hayashi, Satoshi Hatano, Hirofumi Kawakubo, Tai Omori, Seiichiro Ishii, Hitoshi Sugiura

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Reported herein is the case of a 74-year-old man with an unusual gastric carcinoma that developed at the lesser curvature of the stomach. The tumor consisted of small clusters of carcinoma cells surrounded by clear spaces, with histopathology similar to invasive micropapillary carcinoma (IMPC) of the breast. The carcinoma cells, which had downregulation of E-cadherin expression, invaded the subserous tissue and metastasized to the perigastric lymph nodes. IMPC, an unusual subtype of invasive breast carcinoma, is known to have frequent lymph node metastases, resulting in a poor clinical outcome. Although IMPC has been reported in breast, urinary bladder, ureter, lung, salivary gland and colon, to the best of the authors' knowledge this is the first report of IMPC arising in the stomach. Presented here are the clinicopathological features of primary IMPC of the stomach.

Original languageEnglish
Pages (from-to)513-517
Number of pages5
JournalPathology International
Volume58
Issue number8
DOIs
Publication statusPublished - 2008 Aug

Fingerprint

Stomach
Carcinoma
Lymph Nodes
Breast Neoplasms
Small Cell Carcinoma
Cadherins
Ureter
Salivary Glands
Colon
Urinary Bladder
Breast
Down-Regulation
Neoplasm Metastasis
Lung
Neoplasms

Keywords

  • E-cadherin
  • Epithelial membrane antigen
  • Invasive micropapillary carcinoma
  • Stomach

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Primary invasive micropapillary carcinoma of the stomach. / Shimoda, Masayuki; Okada, Yasunori; Hayashi, Yuichiro; Hatano, Satoshi; Kawakubo, Hirofumi; Omori, Tai; Ishii, Seiichiro; Sugiura, Hitoshi.

In: Pathology International, Vol. 58, No. 8, 08.2008, p. 513-517.

Research output: Contribution to journalArticle

Shimoda, Masayuki ; Okada, Yasunori ; Hayashi, Yuichiro ; Hatano, Satoshi ; Kawakubo, Hirofumi ; Omori, Tai ; Ishii, Seiichiro ; Sugiura, Hitoshi. / Primary invasive micropapillary carcinoma of the stomach. In: Pathology International. 2008 ; Vol. 58, No. 8. pp. 513-517.
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