Profile of acotiamide in the treatment of functional dyspepsia

Masahiro Ueda, Eisuke Iwasaki, Hidekazu Suzuki

Research output: Contribution to journalReview articlepeer-review

10 Citations (Scopus)

Abstract

Efficacy of acotiamide for improving symptoms in patients with functional dyspepsia was shown by several clinical trials. In a randomized, double-blind, placebo-controlled, parallel-group comparative Phase III trial conducted in Japan, 100 mg of acotiamide three times a day for 4 weeks was more effective than a placebo for improving symptoms, and quality of life. Acotiamide was well-tolerated treatment, with no significant adverse events. The aim of this review was to summarize the current evidence of the efficacy of acotiamide in the treatment of patients with functional dyspepsia.

Original languageEnglish
Pages (from-to)83-88
Number of pages6
JournalClinical and Experimental Gastroenterology
Volume9
DOIs
Publication statusPublished - 2016 Apr 6

Keywords

  • Acetylcholinesterase
  • Acotiamide
  • Functional dyspepsia
  • Rome III

ASJC Scopus subject areas

  • Gastroenterology

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