Prognostic factors or indicators of gynecologic cancers

Shiro Nozawa, Daisuke Aoki, Kaneyuki Kubushiro, Nobuyuki Susumu, Kouji Banno, Yutaka Tamada

Research output: Contribution to journalArticle

Abstract

The large majority of gynecologic malignancies are comprised of cervical cancer, endometrial cancer and ovarian cancer. Prognostic factors for each disease are based upon various clinical pathological features. These include tumor size and lymph node metastasis for cervical cancer; histological grade, myometrial invasion, and lymph node metastasis for endometrial cancer; histopathological classification, histological grade, and capsule rupture in early ovarian cancer and completeness of debulking surgery in advanced ovarian cancer. In addition to these factors, recent studies have investigated the role of various molecules including growth factors, virus-related molecules, transcription factors, receptors-ligands, cell cycle-related molecules, apoptosis-related molecules as well as various genetic abnormalities as prognostic factors or indicators for gynecologic malignancies. This molecular background of gynecologic cancers will shape future directions in the increasingly individualized basis of treatment.

Original languageEnglish
Pages (from-to)263-271
Number of pages9
JournalBiotherapy
Volume19
Issue number3
Publication statusPublished - 2005 May

Fingerprint

Ovarian Neoplasms
Endometrial Neoplasms
Uterine Cervical Neoplasms
Neoplasms
Lymph Nodes
Neoplasm Metastasis
Capsules
Rupture
Intercellular Signaling Peptides and Proteins
Cell Cycle
Transcription Factors
Apoptosis
Ligands
Viruses
Direction compound

Keywords

  • Cervical cancer
  • Endometrial cancer
  • Ovarian cancer
  • Prognostic factor

ASJC Scopus subject areas

  • Cancer Research
  • Immunology and Allergy

Cite this

Nozawa, S., Aoki, D., Kubushiro, K., Susumu, N., Banno, K., & Tamada, Y. (2005). Prognostic factors or indicators of gynecologic cancers. Biotherapy, 19(3), 263-271.

Prognostic factors or indicators of gynecologic cancers. / Nozawa, Shiro; Aoki, Daisuke; Kubushiro, Kaneyuki; Susumu, Nobuyuki; Banno, Kouji; Tamada, Yutaka.

In: Biotherapy, Vol. 19, No. 3, 05.2005, p. 263-271.

Research output: Contribution to journalArticle

Nozawa, S, Aoki, D, Kubushiro, K, Susumu, N, Banno, K & Tamada, Y 2005, 'Prognostic factors or indicators of gynecologic cancers', Biotherapy, vol. 19, no. 3, pp. 263-271.
Nozawa S, Aoki D, Kubushiro K, Susumu N, Banno K, Tamada Y. Prognostic factors or indicators of gynecologic cancers. Biotherapy. 2005 May;19(3):263-271.
Nozawa, Shiro ; Aoki, Daisuke ; Kubushiro, Kaneyuki ; Susumu, Nobuyuki ; Banno, Kouji ; Tamada, Yutaka. / Prognostic factors or indicators of gynecologic cancers. In: Biotherapy. 2005 ; Vol. 19, No. 3. pp. 263-271.
@article{8129a63a89b94dddb05877fdc49d21b6,
title = "Prognostic factors or indicators of gynecologic cancers",
abstract = "The large majority of gynecologic malignancies are comprised of cervical cancer, endometrial cancer and ovarian cancer. Prognostic factors for each disease are based upon various clinical pathological features. These include tumor size and lymph node metastasis for cervical cancer; histological grade, myometrial invasion, and lymph node metastasis for endometrial cancer; histopathological classification, histological grade, and capsule rupture in early ovarian cancer and completeness of debulking surgery in advanced ovarian cancer. In addition to these factors, recent studies have investigated the role of various molecules including growth factors, virus-related molecules, transcription factors, receptors-ligands, cell cycle-related molecules, apoptosis-related molecules as well as various genetic abnormalities as prognostic factors or indicators for gynecologic malignancies. This molecular background of gynecologic cancers will shape future directions in the increasingly individualized basis of treatment.",
keywords = "Cervical cancer, Endometrial cancer, Ovarian cancer, Prognostic factor",
author = "Shiro Nozawa and Daisuke Aoki and Kaneyuki Kubushiro and Nobuyuki Susumu and Kouji Banno and Yutaka Tamada",
year = "2005",
month = "5",
language = "English",
volume = "19",
pages = "263--271",
journal = "Biotherapy",
issn = "0914-2223",
publisher = "Japanese Society for Cancer Chemotherapy",
number = "3",

}

TY - JOUR

T1 - Prognostic factors or indicators of gynecologic cancers

AU - Nozawa, Shiro

AU - Aoki, Daisuke

AU - Kubushiro, Kaneyuki

AU - Susumu, Nobuyuki

AU - Banno, Kouji

AU - Tamada, Yutaka

PY - 2005/5

Y1 - 2005/5

N2 - The large majority of gynecologic malignancies are comprised of cervical cancer, endometrial cancer and ovarian cancer. Prognostic factors for each disease are based upon various clinical pathological features. These include tumor size and lymph node metastasis for cervical cancer; histological grade, myometrial invasion, and lymph node metastasis for endometrial cancer; histopathological classification, histological grade, and capsule rupture in early ovarian cancer and completeness of debulking surgery in advanced ovarian cancer. In addition to these factors, recent studies have investigated the role of various molecules including growth factors, virus-related molecules, transcription factors, receptors-ligands, cell cycle-related molecules, apoptosis-related molecules as well as various genetic abnormalities as prognostic factors or indicators for gynecologic malignancies. This molecular background of gynecologic cancers will shape future directions in the increasingly individualized basis of treatment.

AB - The large majority of gynecologic malignancies are comprised of cervical cancer, endometrial cancer and ovarian cancer. Prognostic factors for each disease are based upon various clinical pathological features. These include tumor size and lymph node metastasis for cervical cancer; histological grade, myometrial invasion, and lymph node metastasis for endometrial cancer; histopathological classification, histological grade, and capsule rupture in early ovarian cancer and completeness of debulking surgery in advanced ovarian cancer. In addition to these factors, recent studies have investigated the role of various molecules including growth factors, virus-related molecules, transcription factors, receptors-ligands, cell cycle-related molecules, apoptosis-related molecules as well as various genetic abnormalities as prognostic factors or indicators for gynecologic malignancies. This molecular background of gynecologic cancers will shape future directions in the increasingly individualized basis of treatment.

KW - Cervical cancer

KW - Endometrial cancer

KW - Ovarian cancer

KW - Prognostic factor

UR - http://www.scopus.com/inward/record.url?scp=21044432756&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=21044432756&partnerID=8YFLogxK

M3 - Article

VL - 19

SP - 263

EP - 271

JO - Biotherapy

JF - Biotherapy

SN - 0914-2223

IS - 3

ER -