Abstract
We studied the significance for further survival of heart rate variability and other variables in the very elderly. In 1992, we assessed activities of daily living, cognitive function, and nutritional status in 27 centenarians with no disease, in addition to the power of the heart rate variability in the ultralow, very low, low (LF), and high frequency (HF) bands. In 1996, we assessed survival in these centenarians; 17 had died and 10 were still living. Logistic regression analysis using backward elimination detected three factors, dementia, LF/HF, and age, that independently influenced mortality. Mortality risk increased with greater age in 1992, more severe dementia, or lower LF/HF. Sympathetic nerve activity, represented as LF/HF, may be associated with prognosis for survival in centenarians.
| Original language | English |
|---|---|
| Pages (from-to) | 91-97 |
| Number of pages | 7 |
| Journal | Clinical and Experimental Hypertension |
| Volume | 24 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - 2002 |
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Keywords
- Age
- Centenarian
- Dementia
- Heart rate variability
- Prognosis
- Sympathetic nerve function
ASJC Scopus subject areas
- Internal Medicine
Cite this
Prognostic significance of heart rate variability in centenarians. / Shimizu, Kenichiro; Arai, Yasumichi; Hirose, Nobuyoshi; Yonemoto, Takayuki; Wakida, Yasushi.
In: Clinical and Experimental Hypertension, Vol. 24, No. 1-2, 2002, p. 91-97.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prognostic significance of heart rate variability in centenarians
AU - Shimizu, Kenichiro
AU - Arai, Yasumichi
AU - Hirose, Nobuyoshi
AU - Yonemoto, Takayuki
AU - Wakida, Yasushi
PY - 2002
Y1 - 2002
N2 - We studied the significance for further survival of heart rate variability and other variables in the very elderly. In 1992, we assessed activities of daily living, cognitive function, and nutritional status in 27 centenarians with no disease, in addition to the power of the heart rate variability in the ultralow, very low, low (LF), and high frequency (HF) bands. In 1996, we assessed survival in these centenarians; 17 had died and 10 were still living. Logistic regression analysis using backward elimination detected three factors, dementia, LF/HF, and age, that independently influenced mortality. Mortality risk increased with greater age in 1992, more severe dementia, or lower LF/HF. Sympathetic nerve activity, represented as LF/HF, may be associated with prognosis for survival in centenarians.
AB - We studied the significance for further survival of heart rate variability and other variables in the very elderly. In 1992, we assessed activities of daily living, cognitive function, and nutritional status in 27 centenarians with no disease, in addition to the power of the heart rate variability in the ultralow, very low, low (LF), and high frequency (HF) bands. In 1996, we assessed survival in these centenarians; 17 had died and 10 were still living. Logistic regression analysis using backward elimination detected three factors, dementia, LF/HF, and age, that independently influenced mortality. Mortality risk increased with greater age in 1992, more severe dementia, or lower LF/HF. Sympathetic nerve activity, represented as LF/HF, may be associated with prognosis for survival in centenarians.
KW - Age
KW - Centenarian
KW - Dementia
KW - Heart rate variability
KW - Prognosis
KW - Sympathetic nerve function
UR - http://www.scopus.com/inward/record.url?scp=0036171979&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036171979&partnerID=8YFLogxK
U2 - 10.1081/CEH-100108719
DO - 10.1081/CEH-100108719
M3 - Article
VL - 24
SP - 91
EP - 97
JO - Clinical and Experimental Hypertension
JF - Clinical and Experimental Hypertension
SN - 1064-1963
IS - 1-2
ER -