Prognostic significance of pleural lavage cytology immediately after thoracotomy in patients with lung cancer

H. Kondo, Hisao Asamura, K. Suemasu, T. Goya, R. Tsuchiya, T. Naruke, K. Yamagishi, Y. Uei

Research output: Contribution to journalArticle

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Abstract

Pleural lavage cytology immediately after thoracotomy was performed in 467 patients with lung cancer who had little or no pleural effusion. Forty-two patients (9.0%) had positive results. The positivity of pleural lavage cytology was significantly related to the degree of pleural extension of the tumor, microscopic pleural dissemination, cytologic results of minimal pleural effusion, pathologic stage, presence of lymphatic permeation or vascular invasion, and cell type (adenocarcinoma was predominant). The 3- year survival of the patients having negative and positive results of cytology were 68.7% and 22.9%, respectively. The prognosis of the group with positive results was as poor as that of patients with stage IIIB or IV disease. Pleural lavage cytology is an important prognostic factor that indicates microscopic exfoliation of cancer cells into the pleural cavity, that is, subclinical malignant pleural effusion.

Original languageEnglish
Pages (from-to)1092-1097
Number of pages6
JournalJournal of Thoracic and Cardiovascular Surgery
Volume106
Issue number6
Publication statusPublished - 1993
Externally publishedYes

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Therapeutic Irrigation
Thoracotomy
Cell Biology
Lung Neoplasms
Pleural Effusion
Malignant Pleural Effusion
Pleural Cavity
Blood Vessels
Neoplasms
Adenocarcinoma
Survival

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Prognostic significance of pleural lavage cytology immediately after thoracotomy in patients with lung cancer. / Kondo, H.; Asamura, Hisao; Suemasu, K.; Goya, T.; Tsuchiya, R.; Naruke, T.; Yamagishi, K.; Uei, Y.

In: Journal of Thoracic and Cardiovascular Surgery, Vol. 106, No. 6, 1993, p. 1092-1097.

Research output: Contribution to journalArticle

Kondo, H, Asamura, H, Suemasu, K, Goya, T, Tsuchiya, R, Naruke, T, Yamagishi, K & Uei, Y 1993, 'Prognostic significance of pleural lavage cytology immediately after thoracotomy in patients with lung cancer', Journal of Thoracic and Cardiovascular Surgery, vol. 106, no. 6, pp. 1092-1097.
Kondo, H. ; Asamura, Hisao ; Suemasu, K. ; Goya, T. ; Tsuchiya, R. ; Naruke, T. ; Yamagishi, K. ; Uei, Y. / Prognostic significance of pleural lavage cytology immediately after thoracotomy in patients with lung cancer. In: Journal of Thoracic and Cardiovascular Surgery. 1993 ; Vol. 106, No. 6. pp. 1092-1097.
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AU - Tsuchiya, R.

AU - Naruke, T.

AU - Yamagishi, K.

AU - Uei, Y.

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