Proliferation in vitro of melanophores from Xenopus laevis.

Research output: Contribution to journalArticle

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Abstract

Melanophores of wild-type and periodic albino mutants of Xenopus laevis were successfully cultured in vitro. They proliferated in the presence of alpha-melanocyte-stimulating hormone (alpha-MSH or cyclic adenosine monophosphate (cAMP) at a doubling time of 8-10 days. These proliferating melanophores retained their phenotypes, ability to synthesize melanin, and melanin-dispersing response to MSH stimulation. Neither depigmentation nor selective cell death of periodic albino melanophores was observed for at least 4 months during the cultivation.

Original languageEnglish
Pages (from-to)239-244
Number of pages6
JournalJournal of Experimental Zoology
Volume226
Issue number2
Publication statusPublished - 1983 May
Externally publishedYes

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alpha-melanocyte-stimulating hormone
Xenopus laevis
melanin
albino
cyclic AMP
cell death
phenotype
mutants

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

Proliferation in vitro of melanophores from Xenopus laevis. / Fukuzawa, Toshihiko; Ide, H.

In: Journal of Experimental Zoology, Vol. 226, No. 2, 05.1983, p. 239-244.

Research output: Contribution to journalArticle

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