Prostate cancer stem cell and drug resistance

Research output: Contribution to journalArticle

Abstract

Cancer tissues are comprised of cell population including a variety of cells, such as stem cell-like cancer cells, upon which a hierarchical society is constructed. This hypothesis has been applied not only to leukemia, in which the hypothesis was first experimentally confirmed, but also to solid cancers. Recent topics shed light on the modified heterogeneity by various treatments which evolve disease progression. In prostate cancer, the identification of cancer stem cells using surface markers and the relationship with prostate origin are of current interest. This article reviews studies related to the development of prostate cancer and introduce recent progress of our project, focusing on cancer stemness and drug resistance.

Original languageEnglish
Pages (from-to)45-49
Number of pages5
JournalNihon rinsho. Japanese journal of clinical medicine
Volume74
Issue number1
Publication statusPublished - 2016 Jan 1

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Neoplastic Stem Cells
Drug Resistance
Prostatic Neoplasms
Neoplasms
Disease Progression
Prostate
Leukemia
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Prostate cancer stem cell and drug resistance. / Kosaka, Takeo; Oya, Mototsugu.

In: Nihon rinsho. Japanese journal of clinical medicine, Vol. 74, No. 1, 01.01.2016, p. 45-49.

Research output: Contribution to journalArticle

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