Proton beam therapy for children and adolescents and young adults (AYAs): JASTRO and JSPHO Guidelines

Masashi Mizumoto; Hiroshi Fuji; Mitsuru Miyachi; Toshinori Soejima; Tetsuya Yamamoto; Norihiro Aibe; Yusuke Demizu; Hiromitsu Iwata; Takayuki Hashimoto; Atsushi Motegi; Atsufumi Kawamura; Keita Terashima; Takashi Fukushima; Tomohei Nakao; Akinori Takada; Minako Sumi; Junjiro Oshima; Kensuke Moriwaki; Miwako Nozaki; Yuji Ishida; Yoshiyuki Kosaka; Keisuke Ae; Ako Hosono; Hideyuki Harada; Etsuyo Ogo; Tetsuo Akimoto; Takashi Saito; Hiroko Fukushima; Ryoko Suzuki; Mitsuru Takahashi; Takayuki Matsuo; Akira Matsumura; Hidekazu Masaki; Hajime Hosoi; Naoyuki Shigematsu; Hideyuki Sakurai

doi:10.1016/j.ctrv.2021.102209

Proton beam therapy for children and adolescents and young adults (AYAs): JASTRO and JSPHO Guidelines

Masashi Mizumoto, Hiroshi Fuji, Mitsuru Miyachi, Toshinori Soejima, Tetsuya Yamamoto, Norihiro Aibe, Yusuke Demizu, Hiromitsu Iwata, Takayuki Hashimoto, Atsushi Motegi, Atsufumi Kawamura, Keita Terashima, Takashi Fukushima, Tomohei Nakao, Akinori Takada, Minako Sumi, Junjiro Oshima, Kensuke Moriwaki, Miwako Nozaki, Yuji IshidaYoshiyuki Kosaka, Keisuke Ae, Ako Hosono, Hideyuki Harada, Etsuyo Ogo, Tetsuo Akimoto, Takashi Saito, Hiroko Fukushima, Ryoko Suzuki, Mitsuru Takahashi, Takayuki Matsuo, Akira Matsumura, Hidekazu Masaki, Hajime Hosoi, Naoyuki Shigematsu, Hideyuki Sakurai

Department of Radiology (Radiation Oncology)

Research output: Contribution to journal › Review article › peer-review

6 Citations (Scopus)

Abstract

Children and adolescents and young adults (AYAs) with cancer are often treated with a multidisciplinary approach. This includes use of radiotherapy, which is important for local control, but may also cause adverse events in the long term, including second cancer. The risks for limited growth and development, endocrine dysfunction, reduced fertility and second cancer in children and AYAs are reduced by proton beam therapy (PBT), which has a dose distribution that decreases irradiation of normal organs while still targeting the tumor. To define the outcomes and characteristics of PBT in cancer treatment in pediatric and AYA patients, this document was developed by the Japanese Society for Radiation Oncology (JASTRO) and the Japanese Society of Pediatric Hematology/Oncology (JSPHO).

Original language	English
Article number	102209
Journal	Cancer Treatment Reviews
Volume	98
DOIs	https://doi.org/10.1016/j.ctrv.2021.102209
Publication status	Published - 2021 Jul

Keywords

AYA
Children
Guideline
Pediatric
Proton beam therapy

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.ctrv.2021.102209

Cite this

Mizumoto, M., Fuji, H., Miyachi, M., Soejima, T., Yamamoto, T., Aibe, N., Demizu, Y., Iwata, H., Hashimoto, T., Motegi, A., Kawamura, A., Terashima, K., Fukushima, T., Nakao, T., Takada, A., Sumi, M., Oshima, J., Moriwaki, K., Nozaki, M., ... Sakurai, H. (2021). Proton beam therapy for children and adolescents and young adults (AYAs): JASTRO and JSPHO Guidelines. Cancer Treatment Reviews, 98, [102209]. https://doi.org/10.1016/j.ctrv.2021.102209

Mizumoto, M, Fuji, H, Miyachi, M, Soejima, T, Yamamoto, T, Aibe, N, Demizu, Y, Iwata, H, Hashimoto, T, Motegi, A, Kawamura, A, Terashima, K, Fukushima, T, Nakao, T, Takada, A, Sumi, M, Oshima, J, Moriwaki, K, Nozaki, M, Ishida, Y, Kosaka, Y, Ae, K, Hosono, A, Harada, H, Ogo, E, Akimoto, T, Saito, T, Fukushima, H, Suzuki, R, Takahashi, M, Matsuo, T, Matsumura, A, Masaki, H, Hosoi, H, Shigematsu, N & Sakurai, H 2021, 'Proton beam therapy for children and adolescents and young adults (AYAs): JASTRO and JSPHO Guidelines', Cancer Treatment Reviews, vol. 98, 102209. https://doi.org/10.1016/j.ctrv.2021.102209

@article{3282d3fe3ea04e22a08eda2152c8d2bb,

title = "Proton beam therapy for children and adolescents and young adults (AYAs): JASTRO and JSPHO Guidelines",

abstract = "Children and adolescents and young adults (AYAs) with cancer are often treated with a multidisciplinary approach. This includes use of radiotherapy, which is important for local control, but may also cause adverse events in the long term, including second cancer. The risks for limited growth and development, endocrine dysfunction, reduced fertility and second cancer in children and AYAs are reduced by proton beam therapy (PBT), which has a dose distribution that decreases irradiation of normal organs while still targeting the tumor. To define the outcomes and characteristics of PBT in cancer treatment in pediatric and AYA patients, this document was developed by the Japanese Society for Radiation Oncology (JASTRO) and the Japanese Society of Pediatric Hematology/Oncology (JSPHO).",

keywords = "AYA, Children, Guideline, Pediatric, Proton beam therapy",

author = "Masashi Mizumoto and Hiroshi Fuji and Mitsuru Miyachi and Toshinori Soejima and Tetsuya Yamamoto and Norihiro Aibe and Yusuke Demizu and Hiromitsu Iwata and Takayuki Hashimoto and Atsushi Motegi and Atsufumi Kawamura and Keita Terashima and Takashi Fukushima and Tomohei Nakao and Akinori Takada and Minako Sumi and Junjiro Oshima and Kensuke Moriwaki and Miwako Nozaki and Yuji Ishida and Yoshiyuki Kosaka and Keisuke Ae and Ako Hosono and Hideyuki Harada and Etsuyo Ogo and Tetsuo Akimoto and Takashi Saito and Hiroko Fukushima and Ryoko Suzuki and Mitsuru Takahashi and Takayuki Matsuo and Akira Matsumura and Hidekazu Masaki and Hajime Hosoi and Naoyuki Shigematsu and Hideyuki Sakurai",

note = "Funding Information: This work was supported by Children{\textquoteright}s Cancer Association of Japan, and the Japan Agency for Medical Research and Development (AMED) under Grant Number JP 20ck0106610s0801. This work was also partially supported by Grants-in-Aid for Scientific Research (B) (15H04901, 19H03596) from the Ministry of Education, Culture, Sports, Science and Technology of Japan. Publisher Copyright: {\textcopyright} 2021 The Author(s)",

year = "2021",

month = jul,

doi = "10.1016/j.ctrv.2021.102209",

language = "English",

volume = "98",

journal = "Cancer Treatment Reviews",

issn = "0305-7372",

publisher = "W.B. Saunders Ltd",

}

TY - JOUR

T1 - Proton beam therapy for children and adolescents and young adults (AYAs)

T2 - JASTRO and JSPHO Guidelines

AU - Mizumoto, Masashi

AU - Fuji, Hiroshi

AU - Miyachi, Mitsuru

AU - Soejima, Toshinori

AU - Yamamoto, Tetsuya

AU - Aibe, Norihiro

AU - Demizu, Yusuke

AU - Iwata, Hiromitsu

AU - Hashimoto, Takayuki

AU - Motegi, Atsushi

AU - Kawamura, Atsufumi

AU - Terashima, Keita

AU - Fukushima, Takashi

AU - Nakao, Tomohei

AU - Takada, Akinori

AU - Sumi, Minako

AU - Oshima, Junjiro

AU - Moriwaki, Kensuke

AU - Nozaki, Miwako

AU - Ishida, Yuji

AU - Kosaka, Yoshiyuki

AU - Ae, Keisuke

AU - Hosono, Ako

AU - Harada, Hideyuki

AU - Ogo, Etsuyo

AU - Akimoto, Tetsuo

AU - Saito, Takashi

AU - Fukushima, Hiroko

AU - Suzuki, Ryoko

AU - Takahashi, Mitsuru

AU - Matsuo, Takayuki

AU - Matsumura, Akira

AU - Masaki, Hidekazu

AU - Hosoi, Hajime

AU - Shigematsu, Naoyuki

AU - Sakurai, Hideyuki

N1 - Funding Information: This work was supported by Children’s Cancer Association of Japan, and the Japan Agency for Medical Research and Development (AMED) under Grant Number JP 20ck0106610s0801. This work was also partially supported by Grants-in-Aid for Scientific Research (B) (15H04901, 19H03596) from the Ministry of Education, Culture, Sports, Science and Technology of Japan. Publisher Copyright: © 2021 The Author(s)

PY - 2021/7

Y1 - 2021/7

N2 - Children and adolescents and young adults (AYAs) with cancer are often treated with a multidisciplinary approach. This includes use of radiotherapy, which is important for local control, but may also cause adverse events in the long term, including second cancer. The risks for limited growth and development, endocrine dysfunction, reduced fertility and second cancer in children and AYAs are reduced by proton beam therapy (PBT), which has a dose distribution that decreases irradiation of normal organs while still targeting the tumor. To define the outcomes and characteristics of PBT in cancer treatment in pediatric and AYA patients, this document was developed by the Japanese Society for Radiation Oncology (JASTRO) and the Japanese Society of Pediatric Hematology/Oncology (JSPHO).

AB - Children and adolescents and young adults (AYAs) with cancer are often treated with a multidisciplinary approach. This includes use of radiotherapy, which is important for local control, but may also cause adverse events in the long term, including second cancer. The risks for limited growth and development, endocrine dysfunction, reduced fertility and second cancer in children and AYAs are reduced by proton beam therapy (PBT), which has a dose distribution that decreases irradiation of normal organs while still targeting the tumor. To define the outcomes and characteristics of PBT in cancer treatment in pediatric and AYA patients, this document was developed by the Japanese Society for Radiation Oncology (JASTRO) and the Japanese Society of Pediatric Hematology/Oncology (JSPHO).

KW - AYA

KW - Children

KW - Guideline

KW - Pediatric

KW - Proton beam therapy

UR - http://www.scopus.com/inward/record.url?scp=85105526971&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85105526971&partnerID=8YFLogxK

U2 - 10.1016/j.ctrv.2021.102209

DO - 10.1016/j.ctrv.2021.102209

M3 - Review article

C2 - 33984606

AN - SCOPUS:85105526971

SN - 0305-7372

VL - 98

JO - Cancer Treatment Reviews

JF - Cancer Treatment Reviews

M1 - 102209

ER -

Proton beam therapy for children and adolescents and young adults (AYAs): JASTRO and JSPHO Guidelines

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this