PSA nadir after 125I prostate brachytherapy

Atsunori Yorozu, K. Toya, Kayo Yoshida, N. Koike, A. Takahashi, S. Saito, T. Nishiyama, Y. Yagi, R. Namitome, A. Ashikari, T. Kono

Research output: Contribution to journalArticle

Abstract

To evaluate the prostate-specific antigen (PSA) kinetics and nadir of PSA failure after permanent 125I prostate brachytherapy. The study included 660 patients with a potential minimum follow-up of 5 years. Patients who met the Phoenix definition of PSA failure were identified. The PSA decreased gradually to less than 0.2ng/mL even after 5 years for many patients. The median PSA nadir was 0.09ng/mL. Neoadjuvant hormone therapy had little effect on PSA nadir. The PSA nadir < = 0.2ng/mL or current nadir < = 0.4ng/mL seemed to be a good marker as a successful treatment.

Original languageEnglish
Pages (from-to)793-796
Number of pages4
JournalJapanese Journal of Clinical Radiology
Volume57
Issue number6
Publication statusPublished - 2012 Jun 10
Externally publishedYes

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Brachytherapy
Prostate-Specific Antigen
Prostate
Neoadjuvant Therapy
Hormones

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Yorozu, A., Toya, K., Yoshida, K., Koike, N., Takahashi, A., Saito, S., ... Kono, T. (2012). PSA nadir after 125I prostate brachytherapy. Japanese Journal of Clinical Radiology, 57(6), 793-796.

PSA nadir after 125I prostate brachytherapy. / Yorozu, Atsunori; Toya, K.; Yoshida, Kayo; Koike, N.; Takahashi, A.; Saito, S.; Nishiyama, T.; Yagi, Y.; Namitome, R.; Ashikari, A.; Kono, T.

In: Japanese Journal of Clinical Radiology, Vol. 57, No. 6, 10.06.2012, p. 793-796.

Research output: Contribution to journalArticle

Yorozu, A, Toya, K, Yoshida, K, Koike, N, Takahashi, A, Saito, S, Nishiyama, T, Yagi, Y, Namitome, R, Ashikari, A & Kono, T 2012, 'PSA nadir after 125I prostate brachytherapy', Japanese Journal of Clinical Radiology, vol. 57, no. 6, pp. 793-796.
Yorozu A, Toya K, Yoshida K, Koike N, Takahashi A, Saito S et al. PSA nadir after 125I prostate brachytherapy. Japanese Journal of Clinical Radiology. 2012 Jun 10;57(6):793-796.
Yorozu, Atsunori ; Toya, K. ; Yoshida, Kayo ; Koike, N. ; Takahashi, A. ; Saito, S. ; Nishiyama, T. ; Yagi, Y. ; Namitome, R. ; Ashikari, A. ; Kono, T. / PSA nadir after 125I prostate brachytherapy. In: Japanese Journal of Clinical Radiology. 2012 ; Vol. 57, No. 6. pp. 793-796.
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