PSA nadir after 125I prostate brachytherapy

Atsunori Yorozu; K. Toya; K. Yoshida; N. Koike; A. Takahashi; S. Saito; T. Nishiyama; Y. Yagi; R. Namitome; A. Ashikari; T. Kono

PSA nadir after ¹²⁵I prostate brachytherapy

Atsunori Yorozu, K. Toya, K. Yoshida, N. Koike, A. Takahashi, S. Saito, T. Nishiyama, Y. Yagi, R. Namitome, A. Ashikari, T. Kono

Research output: Contribution to journal › Article › peer-review

Abstract

To evaluate the prostate-specific antigen (PSA) kinetics and nadir of PSA failure after permanent ¹²⁵I prostate brachytherapy. The study included 660 patients with a potential minimum follow-up of 5 years. Patients who met the Phoenix definition of PSA failure were identified. The PSA decreased gradually to less than 0.2ng/mL even after 5 years for many patients. The median PSA nadir was 0.09ng/mL. Neoadjuvant hormone therapy had little effect on PSA nadir. The PSA nadir < = 0.2ng/mL or current nadir < = 0.4ng/mL seemed to be a good marker as a successful treatment.

Original language	English
Pages (from-to)	793-796
Number of pages	4
Journal	Japanese Journal of Clinical Radiology
Volume	57
Issue number	6
Publication status	Published - 2012 Jun 10
Externally published	Yes

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Cite this

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title = "PSA nadir after 125I prostate brachytherapy",

abstract = "To evaluate the prostate-specific antigen (PSA) kinetics and nadir of PSA failure after permanent 125I prostate brachytherapy. The study included 660 patients with a potential minimum follow-up of 5 years. Patients who met the Phoenix definition of PSA failure were identified. The PSA decreased gradually to less than 0.2ng/mL even after 5 years for many patients. The median PSA nadir was 0.09ng/mL. Neoadjuvant hormone therapy had little effect on PSA nadir. The PSA nadir < = 0.2ng/mL or current nadir < = 0.4ng/mL seemed to be a good marker as a successful treatment.",

author = "Atsunori Yorozu and K. Toya and K. Yoshida and N. Koike and A. Takahashi and S. Saito and T. Nishiyama and Y. Yagi and R. Namitome and A. Ashikari and T. Kono",

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T1 - PSA nadir after 125I prostate brachytherapy

AU - Yorozu, Atsunori

AU - Toya, K.

AU - Yoshida, K.

AU - Koike, N.

AU - Takahashi, A.

AU - Saito, S.

AU - Nishiyama, T.

AU - Yagi, Y.

AU - Namitome, R.

AU - Ashikari, A.

AU - Kono, T.

PY - 2012/6/10

Y1 - 2012/6/10

N2 - To evaluate the prostate-specific antigen (PSA) kinetics and nadir of PSA failure after permanent 125I prostate brachytherapy. The study included 660 patients with a potential minimum follow-up of 5 years. Patients who met the Phoenix definition of PSA failure were identified. The PSA decreased gradually to less than 0.2ng/mL even after 5 years for many patients. The median PSA nadir was 0.09ng/mL. Neoadjuvant hormone therapy had little effect on PSA nadir. The PSA nadir < = 0.2ng/mL or current nadir < = 0.4ng/mL seemed to be a good marker as a successful treatment.

AB - To evaluate the prostate-specific antigen (PSA) kinetics and nadir of PSA failure after permanent 125I prostate brachytherapy. The study included 660 patients with a potential minimum follow-up of 5 years. Patients who met the Phoenix definition of PSA failure were identified. The PSA decreased gradually to less than 0.2ng/mL even after 5 years for many patients. The median PSA nadir was 0.09ng/mL. Neoadjuvant hormone therapy had little effect on PSA nadir. The PSA nadir < = 0.2ng/mL or current nadir < = 0.4ng/mL seemed to be a good marker as a successful treatment.

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PSA nadir after ¹²⁵I prostate brachytherapy

Abstract

ASJC Scopus subject areas

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