Pupillary response to tropicamide in Japanese patients with alcoholic dementia, Alzheimer's disease, and vascular dementia

Susumu Higuchi, Sachio Matsushita, Yoshio Hasegawa, Taro Muramatsu, Hiroyuki Arai

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The anticholinergic agent tropicamide causes a significantly greater change in the pupil diameter of patients with Alzheimer's disease (AD) than in that of patients with alcoholic or vascular dementia or in normal controls. Although the response increases with the severity of AD, the overlap of response with normal controls in milder cases and the difficulty of obtaining results in severe cases limit its use as a diagnostic tool.

Original languageEnglish
Pages (from-to)199-201
Number of pages3
JournalExperimental Neurology
Volume144
Issue number1
DOIs
Publication statusPublished - 1997 Mar
Externally publishedYes

ASJC Scopus subject areas

  • Neurology
  • Developmental Neuroscience

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