Quality of life in adult patients after stem cell transplantation

Kunio Yano, T. Kanie, Shinichiro Okamoto, H. Kojima, T. Yoshida, I. Maruta, H. Dohi, Y. Morishita, K. Ozawa, H. Sao, H. Sakamaki, S. Hiraoka, S. Imoto, Y. Morishima, Y. Kodera

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Many articles pertaining to quality of life (QOL) following stem cell transplantation have been published in the US and western Europe. However, since the actions of health insurance systems and overall cultural aspects are strongly associated with QOL, investigations into QOL should be carried out within all countries. Therefore, we have investigated the QOL of adult patients following stem cell transplantation at 31 hospitals in Japan. The survivors, who were surveyed by mail questionnaire, were 20 years or older at the time of this study. The underlying diseases were acute lymphoblastic leukemia, acute myelogenous leukemia, chronic myelogenous leukemia, non-Hodgkin's lymphoma, Hodgkin's disease, myelodysplastic syndrome, and multiple myeloma. Median age at the time of the study was 36 years, and median interval after transplantation was 35.3 months. Of 383 patients surveyed, 282 (73.6%) responded to the questionnaire. One hundred and ninety-two patients were treated with an allogeneic-related transplantation, 52 with allogeneic-unrelated, and 38 with an autologous transplantation. Our data revealed that the length of time since transplantation and the diagnosis of chronic GVHD were associated with QOL. When unrelated and related transplantation recipients were compared, ratings on relief from pain, stability in weight, and confidence in dealing with daily life were lower among unrelated transplantation patients.

Original languageEnglish
Pages (from-to)283-289
Number of pages7
JournalInternational Journal of Hematology
Volume71
Issue number3
Publication statusPublished - 2000
Externally publishedYes

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Stem Cell Transplantation
Quality of Life
Transplantation
Time and Motion Studies
Autologous Transplantation
Myelodysplastic Syndromes
Homologous Transplantation
Postal Service
Health Insurance
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Multiple Myeloma
Hodgkin Disease
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Acute Myeloid Leukemia
Non-Hodgkin's Lymphoma
Survivors
Japan
Weights and Measures
Pain
Surveys and Questionnaires

Keywords

  • Functional living index-cancer (FLIC)
  • Quality of life (QOL)
  • Stem cell transplantation

ASJC Scopus subject areas

  • Hematology

Cite this

Yano, K., Kanie, T., Okamoto, S., Kojima, H., Yoshida, T., Maruta, I., ... Kodera, Y. (2000). Quality of life in adult patients after stem cell transplantation. International Journal of Hematology, 71(3), 283-289.

Quality of life in adult patients after stem cell transplantation. / Yano, Kunio; Kanie, T.; Okamoto, Shinichiro; Kojima, H.; Yoshida, T.; Maruta, I.; Dohi, H.; Morishita, Y.; Ozawa, K.; Sao, H.; Sakamaki, H.; Hiraoka, S.; Imoto, S.; Morishima, Y.; Kodera, Y.

In: International Journal of Hematology, Vol. 71, No. 3, 2000, p. 283-289.

Research output: Contribution to journalArticle

Yano, K, Kanie, T, Okamoto, S, Kojima, H, Yoshida, T, Maruta, I, Dohi, H, Morishita, Y, Ozawa, K, Sao, H, Sakamaki, H, Hiraoka, S, Imoto, S, Morishima, Y & Kodera, Y 2000, 'Quality of life in adult patients after stem cell transplantation', International Journal of Hematology, vol. 71, no. 3, pp. 283-289.
Yano K, Kanie T, Okamoto S, Kojima H, Yoshida T, Maruta I et al. Quality of life in adult patients after stem cell transplantation. International Journal of Hematology. 2000;71(3):283-289.
Yano, Kunio ; Kanie, T. ; Okamoto, Shinichiro ; Kojima, H. ; Yoshida, T. ; Maruta, I. ; Dohi, H. ; Morishita, Y. ; Ozawa, K. ; Sao, H. ; Sakamaki, H. ; Hiraoka, S. ; Imoto, S. ; Morishima, Y. ; Kodera, Y. / Quality of life in adult patients after stem cell transplantation. In: International Journal of Hematology. 2000 ; Vol. 71, No. 3. pp. 283-289.
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