Abstract
Background: Controlling and decreasing the heart rate (HR) of patients during coronary computed tomography angiography (CCTA) is necessary to reduce radiation exposure and improve image quality. This prospective multicenter study aimed to investigate whether HR control with landiolol hydrochloride is useful for reducing radiation exposure during CCTA. Methods and Results: We investigated 219 patients with suspected ischemic heart disease whose pretest HRs were 50–80 beats/min. We measured the HR before and after administration of landiolol hydrochloride and compared the estimated exposure inferred from the HR before administration of landiolol hydrochloride with the actual dose. After administration of landiolol hydrochloride, the mean HR (59.9 ± 6.4 beats/min) at the time of CCTA was significantly lower than before administration (69.3 ± 7.3 beats/min; P
| Original language | English |
|---|---|
| Pages (from-to) | 1225-1231 |
| Number of pages | 7 |
| Journal | Circulation Journal |
| Volume | 80 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2016 |
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Keywords
- Beta-blockers
- Coronary computed tomography angiography
- Ischemic heart disease
- Landiolol hydrochloride
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Radiation-dose-lowering effects of landiolol hydrochloride in coronary angiography using computed tomography (DELIGHT) : A prospective multicenter study. / Kido, Teruhito; Mochizuki, Teruhito; Hirano, Masaharu; Yamada, Yoshitake; Tanaka, Ryoichi; Kanzaki, Suzu; Higashi, Masahiro; Jinzaki, Masahiro; Yoshioka, Kunihiro; Kuribayashi, Sachio.
In: Circulation Journal, Vol. 80, No. 5, 2016, p. 1225-1231.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Radiation-dose-lowering effects of landiolol hydrochloride in coronary angiography using computed tomography (DELIGHT)
T2 - A prospective multicenter study
AU - Kido, Teruhito
AU - Mochizuki, Teruhito
AU - Hirano, Masaharu
AU - Yamada, Yoshitake
AU - Tanaka, Ryoichi
AU - Kanzaki, Suzu
AU - Higashi, Masahiro
AU - Jinzaki, Masahiro
AU - Yoshioka, Kunihiro
AU - Kuribayashi, Sachio
PY - 2016
Y1 - 2016
N2 - Background: Controlling and decreasing the heart rate (HR) of patients during coronary computed tomography angiography (CCTA) is necessary to reduce radiation exposure and improve image quality. This prospective multicenter study aimed to investigate whether HR control with landiolol hydrochloride is useful for reducing radiation exposure during CCTA. Methods and Results: We investigated 219 patients with suspected ischemic heart disease whose pretest HRs were 50–80 beats/min. We measured the HR before and after administration of landiolol hydrochloride and compared the estimated exposure inferred from the HR before administration of landiolol hydrochloride with the actual dose. After administration of landiolol hydrochloride, the mean HR (59.9 ± 6.4 beats/min) at the time of CCTA was significantly lower than before administration (69.3 ± 7.3 beats/min; P
AB - Background: Controlling and decreasing the heart rate (HR) of patients during coronary computed tomography angiography (CCTA) is necessary to reduce radiation exposure and improve image quality. This prospective multicenter study aimed to investigate whether HR control with landiolol hydrochloride is useful for reducing radiation exposure during CCTA. Methods and Results: We investigated 219 patients with suspected ischemic heart disease whose pretest HRs were 50–80 beats/min. We measured the HR before and after administration of landiolol hydrochloride and compared the estimated exposure inferred from the HR before administration of landiolol hydrochloride with the actual dose. After administration of landiolol hydrochloride, the mean HR (59.9 ± 6.4 beats/min) at the time of CCTA was significantly lower than before administration (69.3 ± 7.3 beats/min; P
KW - Beta-blockers
KW - Coronary computed tomography angiography
KW - Ischemic heart disease
KW - Landiolol hydrochloride
UR - http://www.scopus.com/inward/record.url?scp=84964211518&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84964211518&partnerID=8YFLogxK
U2 - 10.1253/circj.CJ-15-0962
DO - 10.1253/circj.CJ-15-0962
M3 - Article
VL - 80
SP - 1225
EP - 1231
JO - Circulation Journal
JF - Circulation Journal
SN - 1346-9843
IS - 5
ER -