Radiation therapy for idiopathic orbital myositis: Two case reports and literature review

Koichi Isobe, Takashi Uno, Hiroyuki Kawakami, Naoyuki Ueno, Tetsuya Kawata, Hideki Abe, Katsuyuki Minowa, Shuichi Yamamoto, Hisao Ito

Research output: Contribution to journalReview article

23 Citations (Scopus)

Abstract

We report two cases of idiopathic orbital myositis treated with radiation therapy (RT). Both patients visited our hospital with complaints of orbital pain on eye movement and eyelid swelling. There was no history of thyroid disease or trauma, and no signs of infection, neoplasm, or collagen disease. The laboratory investigations, including a thyroid function test, showed no abnormalities in either woman. They were initially treated with a combination of corticosteroids (CS) and nonsteroidal anti-inflammatory drugs (NSAIDs), however, they became dependent on or refractory to oral CS therapy, and received 20 Gy in 10 fractions of RT to the orbit. Their symptoms decreased immediately, and both patients were able to reduce the dosage of oral CS after RT. One patient could completely withdraw oral CS thereafter. However, they both experienced recurrence at eight months after RT, and have been receiving oral CS to control their symptoms. RT at doses of 20 Gy in 10 fractions for patients with idiopathic orbital myositis appears to be effective in palliating symptoms, but long-term control is not satisfactory.

Original languageEnglish
Pages (from-to)429-431
Number of pages3
JournalRadiation Medicine - Medical Imaging and Radiation Oncology
Volume22
Issue number6
Publication statusPublished - 2004 Nov 1

Keywords

  • Idiopathic orbital myositis
  • Radiation therapy
  • Steroid

ASJC Scopus subject areas

  • Radiation
  • Radiology Nuclear Medicine and imaging
  • Oncology

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    Isobe, K., Uno, T., Kawakami, H., Ueno, N., Kawata, T., Abe, H., Minowa, K., Yamamoto, S., & Ito, H. (2004). Radiation therapy for idiopathic orbital myositis: Two case reports and literature review. Radiation Medicine - Medical Imaging and Radiation Oncology, 22(6), 429-431.