Random Chiral Asymmetry Generation by Chiral Autocatalysis in a Far-from-equilibrium Reaction System

Kouichi Asakura, Akihito Ikumo, Kazuyuki Kurihara, Shuichi Osanai, Dilip K. Kondepudi

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

If the growth in a local concentration due to an autocatalytic process overcomes diffusion, a concentration fluctuation in a small volume will grow. In a chirally autocatalytic system, this phenomenon could produce a large variation in the enantiomeric excess (ee). Here we report kinetic studies that show such stochastic behavior in the synthesis of an autocatalytic chiral cobalt complex. The established values of the kinetic parameters indicate that temperature inhomogeneities in the form of local hot spots can have a significant effect on the progress of the reaction as well as the ee of the final product. Stochastic kinetics of this type are in stark contrast to deterministic kinetics that are usually encountered in chemistry; in these systems random fluctuations play an important role in determining the product distribution. In the present case we find large random fluctuations in the ee.

Original languageEnglish
Pages (from-to)2689-2694
Number of pages6
JournalJournal of Physical Chemistry A
Volume104
Issue number12
DOIs
Publication statusPublished - 2000 Mar 30

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry

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