Random-walk mechanism in the genetic recombination

Youhei Fujitani, Junji Kawai, Ichizo Kobayashi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We have explained some experimental data of the homologous recombination and the genetic interference in terms of one-dimensional random walk over discrete sites. We first review our previous results. Next, we modify our random-walk model for the homologous recombination into a continuous-site model, and discuss a possible explanation for the previous experimental data obtained by means of the plasmid having one-side homology. Finally, we show that a reaction between an intermediate and a product is indispensable in explaining the genetic interference in terms of our reaction-diffusion model.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
Pages275-282
Number of pages8
Volume680
DOIs
Publication statusPublished - 2010

Publication series

NameAdvances in Experimental Medicine and Biology
Volume680
ISSN (Print)00652598

Fingerprint

Homologous Recombination
Genetic Recombination
Plasmids

Keywords

  • Genetic interference
  • Homologous recombination
  • Homology
  • Plasmid
  • Random walk model
  • Reaction-diffusion model

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Fujitani, Y., Kawai, J., & Kobayashi, I. (2010). Random-walk mechanism in the genetic recombination. In Advances in Experimental Medicine and Biology (Vol. 680, pp. 275-282). (Advances in Experimental Medicine and Biology; Vol. 680). https://doi.org/10.1007/978-1-4419-5913-3_31

Random-walk mechanism in the genetic recombination. / Fujitani, Youhei; Kawai, Junji; Kobayashi, Ichizo.

Advances in Experimental Medicine and Biology. Vol. 680 2010. p. 275-282 (Advances in Experimental Medicine and Biology; Vol. 680).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fujitani, Y, Kawai, J & Kobayashi, I 2010, Random-walk mechanism in the genetic recombination. in Advances in Experimental Medicine and Biology. vol. 680, Advances in Experimental Medicine and Biology, vol. 680, pp. 275-282. https://doi.org/10.1007/978-1-4419-5913-3_31
Fujitani Y, Kawai J, Kobayashi I. Random-walk mechanism in the genetic recombination. In Advances in Experimental Medicine and Biology. Vol. 680. 2010. p. 275-282. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-1-4419-5913-3_31
Fujitani, Youhei ; Kawai, Junji ; Kobayashi, Ichizo. / Random-walk mechanism in the genetic recombination. Advances in Experimental Medicine and Biology. Vol. 680 2010. pp. 275-282 (Advances in Experimental Medicine and Biology).
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