Rational use of oral antibiotics for pediatric infections

K. Sunakawa, H. Akita, S. Iwata, Y. Sato, R. Fujii

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

We carried out a survey in Japan to investigate compliance among children given oral antibiotics in an outpatient setting. The results of our survey revealed that, in Japan, approximately one-quarter of patients did not take their full course of antibiotics. Reasons for unsupervised self-discontinuation included: (1) the parent or guardian judged the infection to be cured; (2) the child refused to take the drug; and (3) the appearance of side effects. Causative organisms often involved in respiratory infections experienced in outpatient medicine include pneumococci, streptococci, staphylococci, Haemophilus influenzae, Moraxella (Branhamella) catarrhalis and Mycoplasma pneumoniae. The β-lactams are effective against all of these bacterial species, with the exception of M. pneumoniae. We conducted a survey of β-lactam antibiotics currently on the Japanese market and compared them to other oral antibiotics used to treat respiratory infections. Ease of administration, based on the incidence of adverse effects, particularly diarrhea, the dosage form, taste, dosage per administration and the number of doses required per day, are reported.

Original languageEnglish
JournalInfection
Volume23
Issue number2 Supplement
DOIs
Publication statusPublished - 1995 Mar
Externally publishedYes

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Pediatrics
Anti-Bacterial Agents
Lactams
Mycoplasma pneumoniae
Infection
Respiratory Tract Infections
Japan
Outpatients
Moraxella (Branhamella) catarrhalis
Dosage Forms
Haemophilus influenzae
Streptococcus pneumoniae
Streptococcus
Staphylococcus
Compliance
Diarrhea
Medicine
Incidence
Pharmaceutical Preparations
Surveys and Questionnaires

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology

Cite this

Sunakawa, K., Akita, H., Iwata, S., Sato, Y., & Fujii, R. (1995). Rational use of oral antibiotics for pediatric infections. Infection, 23(2 Supplement). https://doi.org/10.1007/BF01742988

Rational use of oral antibiotics for pediatric infections. / Sunakawa, K.; Akita, H.; Iwata, S.; Sato, Y.; Fujii, R.

In: Infection, Vol. 23, No. 2 Supplement, 03.1995.

Research output: Contribution to journalArticle

Sunakawa, K, Akita, H, Iwata, S, Sato, Y & Fujii, R 1995, 'Rational use of oral antibiotics for pediatric infections', Infection, vol. 23, no. 2 Supplement. https://doi.org/10.1007/BF01742988
Sunakawa K, Akita H, Iwata S, Sato Y, Fujii R. Rational use of oral antibiotics for pediatric infections. Infection. 1995 Mar;23(2 Supplement). https://doi.org/10.1007/BF01742988
Sunakawa, K. ; Akita, H. ; Iwata, S. ; Sato, Y. ; Fujii, R. / Rational use of oral antibiotics for pediatric infections. In: Infection. 1995 ; Vol. 23, No. 2 Supplement.
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