Reaction of 2,2,5,7,8-pentamethyl-6-chromanol, an α-tocopherol analogue, with NO in the presence of oxygen

Yoshiko Nagata, Tamamo Nishio, Shigenobu Matsumoto, Hideko Kanazawa, Masataka Mochizuki, Yoshikazu Matsushima

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

An α-tocopherol model compound, 2,2,5,7,8-pentamethyl-6-chromanol, reacted with nitric oxide (NO) in the presence of various amounts of oxygen to afford four major products. Distribution of the products was varied depending on the ratio of NO and O2, and the preincubation time of NO and O2. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)2709-2712
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume10
Issue number24
DOIs
Publication statusPublished - 2000 Dec 18

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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