Reaction of 2,2,5,7,8-pentamethyl-6-chromanol, an α-tocopherol analogue, with NO in the presence of oxygen

Yoshiko Nagata; Tamamo Nishio; Shigenobu Matsumoto; Hideko Kanazawa; Masataka Mochizuki; Yoshikazu Matsushima

doi:10.1016/S0960-894X(00)00563-1

Reaction of 2,2,5,7,8-pentamethyl-6-chromanol, an α-tocopherol analogue, with NO in the presence of oxygen

Yoshiko Nagata, Tamamo Nishio, Shigenobu Matsumoto, Hideko Kanazawa, Masataka Mochizuki, Yoshikazu Matsushima

School of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

An α-tocopherol model compound, 2,2,5,7,8-pentamethyl-6-chromanol, reacted with nitric oxide (NO) in the presence of various amounts of oxygen to afford four major products. Distribution of the products was varied depending on the ratio of NO and O₂, and the preincubation time of NO and O₂. (C) 2000 Elsevier Science Ltd.

Original language	English
Pages (from-to)	2709-2712
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	10
Issue number	24
DOIs	https://doi.org/10.1016/S0960-894X(00)00563-1
Publication status	Published - 2000 Dec 18

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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title = "Reaction of 2,2,5,7,8-pentamethyl-6-chromanol, an α-tocopherol analogue, with NO in the presence of oxygen",

abstract = "An α-tocopherol model compound, 2,2,5,7,8-pentamethyl-6-chromanol, reacted with nitric oxide (NO) in the presence of various amounts of oxygen to afford four major products. Distribution of the products was varied depending on the ratio of NO and O2, and the preincubation time of NO and O2. (C) 2000 Elsevier Science Ltd.",

author = "Yoshiko Nagata and Tamamo Nishio and Shigenobu Matsumoto and Hideko Kanazawa and Masataka Mochizuki and Yoshikazu Matsushima",

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AU - Nagata, Yoshiko

AU - Nishio, Tamamo

AU - Matsumoto, Shigenobu

AU - Kanazawa, Hideko

AU - Mochizuki, Masataka

AU - Matsushima, Yoshikazu

PY - 2000/12/18

Y1 - 2000/12/18

N2 - An α-tocopherol model compound, 2,2,5,7,8-pentamethyl-6-chromanol, reacted with nitric oxide (NO) in the presence of various amounts of oxygen to afford four major products. Distribution of the products was varied depending on the ratio of NO and O2, and the preincubation time of NO and O2. (C) 2000 Elsevier Science Ltd.

AB - An α-tocopherol model compound, 2,2,5,7,8-pentamethyl-6-chromanol, reacted with nitric oxide (NO) in the presence of various amounts of oxygen to afford four major products. Distribution of the products was varied depending on the ratio of NO and O2, and the preincubation time of NO and O2. (C) 2000 Elsevier Science Ltd.

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ER -

Reaction of 2,2,5,7,8-pentamethyl-6-chromanol, an α-tocopherol analogue, with NO in the presence of oxygen

Abstract

ASJC Scopus subject areas

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