Reaction of 2,2,5,7,8-pentamethyl-6-chromanol, an α-tocopherol analogue, with NO in the presence of oxygen

Yoshiko Itoh, Tamamo Nishio, Shigenobu Matsumoto, Hideko Kanazawa, Masataka Mochizuki, Yoshikazu Matsushima

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

An α-tocopherol model compound, 2,2,5,7,8-pentamethyl-6-chromanol, reacted with nitric oxide (NO) in the presence of various amounts of oxygen to afford four major products. Distribution of the products was varied depending on the ratio of NO and O2, and the preincubation time of NO and O2. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)2709-2712
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume10
Issue number24
Publication statusPublished - 2000 Dec 18

Fingerprint

Tocopherols
Nitric Oxide
Oxygen
2,2,5,7,8-pentamethyl-1-hydroxychroman

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science

Cite this

Reaction of 2,2,5,7,8-pentamethyl-6-chromanol, an α-tocopherol analogue, with NO in the presence of oxygen. / Itoh, Yoshiko; Nishio, Tamamo; Matsumoto, Shigenobu; Kanazawa, Hideko; Mochizuki, Masataka; Matsushima, Yoshikazu.

In: Bioorganic and Medicinal Chemistry Letters, Vol. 10, No. 24, 18.12.2000, p. 2709-2712.

Research output: Contribution to journalArticle

Itoh, Yoshiko ; Nishio, Tamamo ; Matsumoto, Shigenobu ; Kanazawa, Hideko ; Mochizuki, Masataka ; Matsushima, Yoshikazu. / Reaction of 2,2,5,7,8-pentamethyl-6-chromanol, an α-tocopherol analogue, with NO in the presence of oxygen. In: Bioorganic and Medicinal Chemistry Letters. 2000 ; Vol. 10, No. 24. pp. 2709-2712.
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