Reaction of 2,2,5,7,8-pentamethyl-6-chromanol, an α-tocopherol analogue, with NO in the presence of oxygen

Yoshiko Nagata, Tamamo Nishio, Shigenobu Matsumoto, Hideko Kanazawa, Masataka Mochizuki, Yoshikazu Matsushima

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An α-tocopherol model compound, 2,2,5,7,8-pentamethyl-6-chromanol, reacted with nitric oxide (NO) in the presence of various amounts of oxygen to afford four major products. Distribution of the products was varied depending on the ratio of NO and O2, and the preincubation time of NO and O2. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)2709-2712
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Issue number24
Publication statusPublished - 2000 Dec 18


ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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