Recent advances in the synthesis of morphine and related alkaloids

Research output: Chapter in Book/Report/Conference proceedingChapter

25 Citations (Scopus)

Abstract

Morphine, an alkaloid isolated from the opium poppy, has been widely used as an analgesic, and has been a fascinating synthetic target of organic chemists. After the first total synthesis reported in 1952, a number of synthetic studies toward morphine have been reported, and findings obtained in such studies have greatly contributed to the progress of synthetic organic chemistry as well as medicinal chemistry. This review provides an overview of recent studies toward the total synthesis of morphine and related alkaloids. Work reported in the literature since 2004 will be reviewed.

Original languageEnglish
Title of host publicationTopics in Current Chemistry
Pages1-28
Number of pages28
Volume299
DOIs
Publication statusPublished - 2011

Publication series

NameTopics in Current Chemistry
Volume299
ISSN (Print)03401022

Fingerprint

Alkaloids
Morphine
Opium
Analgesics

Keywords

  • Chiral synthesis
  • Codeine
  • Morphine
  • Total synthesis

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Chida, N. (2011). Recent advances in the synthesis of morphine and related alkaloids. In Topics in Current Chemistry (Vol. 299, pp. 1-28). (Topics in Current Chemistry; Vol. 299). https://doi.org/10.1007/128_2010_73

Recent advances in the synthesis of morphine and related alkaloids. / Chida, Noritaka.

Topics in Current Chemistry. Vol. 299 2011. p. 1-28 (Topics in Current Chemistry; Vol. 299).

Research output: Chapter in Book/Report/Conference proceedingChapter

Chida, N 2011, Recent advances in the synthesis of morphine and related alkaloids. in Topics in Current Chemistry. vol. 299, Topics in Current Chemistry, vol. 299, pp. 1-28. https://doi.org/10.1007/128_2010_73
Chida N. Recent advances in the synthesis of morphine and related alkaloids. In Topics in Current Chemistry. Vol. 299. 2011. p. 1-28. (Topics in Current Chemistry). https://doi.org/10.1007/128_2010_73
Chida, Noritaka. / Recent advances in the synthesis of morphine and related alkaloids. Topics in Current Chemistry. Vol. 299 2011. pp. 1-28 (Topics in Current Chemistry).
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