Reconstruction of capillary networks in HUVEC-MSC coculture cultured in static/flow conditions in a microfluidic platform

Kohei Tanimura, Kyoko Yamamoto, Ryo Sudo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

There is a demand for creating stabilized capillary structures covered by pericytes in the field of tissue engineering. In this study, we performed coculture of human umbilical vein endothelial cells (HUVEC) and mesenchymal stem cells (MSC) in a microfluidic platform to investigate the effect of static/flow conditions on constructing capillaries with aligning pericytes. The results indicated that capillary formation was attenuated in flow conditions in HUVEC-MSC coculture.

Original languageEnglish
Title of host publication17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PublisherChemical and Biological Microsystems Society
Pages1722-1724
Number of pages3
ISBN (Print)9781632666246
Publication statusPublished - 2013 Jan 1
Event17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
Duration: 2013 Oct 272013 Oct 31

Publication series

Name17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Volume3

Other

Other17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
CountryGermany
CityFreiburg
Period13/10/2713/10/31

Keywords

  • Angiogenesis
  • HUVEC
  • MSC
  • Microfluidic platform

ASJC Scopus subject areas

  • Bioengineering

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  • Cite this

    Tanimura, K., Yamamoto, K., & Sudo, R. (2013). Reconstruction of capillary networks in HUVEC-MSC coculture cultured in static/flow conditions in a microfluidic platform. In 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 (pp. 1722-1724). (17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; Vol. 3). Chemical and Biological Microsystems Society.