Recovery of vision following enzyme replacement therapy in a patient with mucopolysaccharidosis type II, hunter syndrome

Ryutaro Yamanishi, Natsuko Nakamura, Kazushige Tsunoda

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

We analyzed the effects of enzyme replacement therapy (ERT) on the visual acuity and visual fields of a patient with mucopolysaccharidosis type II, Hunter syndrome, with degeneration of the retina and abnormalities of the optic nerve. After the ERT, there was an improvement of the visual acuity and visual fields and an improvement of the activities of daily living. Despite the late onset of Hunter syndrome in this patient, ERT was still able to improve the visual function. We conclude that ERT should be considered regardless of the age of the manifestations of the signs and symptoms of Hunter syndrome.

Original languageEnglish
Pages (from-to)186-194
Number of pages9
JournalCase Reports in Ophthalmology
Volume10
Issue number2
DOIs
Publication statusPublished - 2019 May 1

Keywords

  • Enzyme replacement therapy
  • Hunter syndrome
  • Idursulfase
  • Mucopolysaccharidosis type II
  • Recovery
  • Vision

ASJC Scopus subject areas

  • Ophthalmology

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