Recurrent inhibition model of cat gastrocnemius muscle

Takanori Uchiyama, Uwe Windhorst, Håkan Johansson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The purpose of this study was to construct a time domain model of cat medial gastrocnemus muscle with recurrent inhibition by Renshaw cells. The model consists of 300 motoneurons, 300 Renshaw cells and 300 muscle units. The membrane potential was calculated by convoluting EPSP (excitatory post-synaptic potential) caused by the descending command inputs, the AHP (after hyperpolarization) observed after the firing of the motoneurons and the IPSP (inhibitory post-synaptic potential) from Renshaw cells. When the membrane potential reaches the threshold potential, the motoneurons send an exitatory impulse to muscle units and Renshaw cells. The muscle units generate force and the Renshaw cells generate inhibitory burst pulse trains back to the motoneurons. The static firing rate of Renshaw cells of the proposed model was well approximated with the function which was investigated by physiological experiments.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages1984-1985
Number of pages2
Volume3
Publication statusPublished - 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: 2002 Oct 232002 Oct 26

Other

OtherProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS)
CountryUnited States
CityHouston, TX
Period02/10/2302/10/26

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Keywords

  • Cat
  • Gastrocnemius
  • Motoneuron
  • Recurrent inhibition
  • Renshaw cell

ASJC Scopus subject areas

  • Bioengineering

Cite this

Uchiyama, T., Windhorst, U., & Johansson, H. (2002). Recurrent inhibition model of cat gastrocnemius muscle. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 3, pp. 1984-1985)