Reduced intensity regimen for a second mismatched transplant

T. Saito; F. Nakamura; Y. Kanda; R. Tanosaki; Y. Takaue; S. Mineishi

Reduced intensity regimen for a second mismatched transplant

T. Saito, F. Nakamura, Y. Kanda, R. Tanosaki, Y. Takaue, S. Mineishi

Research output: Contribution to journal › Article › peer-review

Abstract

In this report we describe our experience with two patients in order to evaluate the clinical potential of a reduced intensity stem cell transplantation in a more difficult clinical setting, i.e. second transplant with a one- or two-antigen mismatched related donor for relapsed and refractory leukemia. Three benefits were hoped for: 1) reduced regimen-related toxicity, 2) potent engraftment facilitation, and 3) an intense anti-leukemia effect.

Original language	English
Pages (from-to)	780-781
Number of pages	2
Journal	Haematologica
Volume	86
Issue number	7
Publication status	Published - 2001 Aug 7
Externally published	Yes

Keywords

Mismatch
Reduced-intensity transplant
Second transplant

ASJC Scopus subject areas

Hematology

Cite this

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AU - Saito, T.

AU - Nakamura, F.

AU - Kanda, Y.

AU - Tanosaki, R.

AU - Takaue, Y.

AU - Mineishi, S.

PY - 2001/8/7

Y1 - 2001/8/7

N2 - In this report we describe our experience with two patients in order to evaluate the clinical potential of a reduced intensity stem cell transplantation in a more difficult clinical setting, i.e. second transplant with a one- or two-antigen mismatched related donor for relapsed and refractory leukemia. Three benefits were hoped for: 1) reduced regimen-related toxicity, 2) potent engraftment facilitation, and 3) an intense anti-leukemia effect.

AB - In this report we describe our experience with two patients in order to evaluate the clinical potential of a reduced intensity stem cell transplantation in a more difficult clinical setting, i.e. second transplant with a one- or two-antigen mismatched related donor for relapsed and refractory leukemia. Three benefits were hoped for: 1) reduced regimen-related toxicity, 2) potent engraftment facilitation, and 3) an intense anti-leukemia effect.

KW - Mismatch

KW - Reduced-intensity transplant

KW - Second transplant

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IS - 7

ER -

Reduced intensity regimen for a second mismatched transplant

Abstract

Keywords

ASJC Scopus subject areas

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