TY - JOUR
T1 - Regioselective and stereoselective glycosylations utilizing organoboron compounds
AU - Takahashi, Daisuke
AU - Tanaka, Masamichi
AU - Toshima, Kazunobu
N1 - Funding Information:
The authors want to thank all the co-workers who have worked on our projects presented here. Our research presented here was supported in part by the MEXT-supported Program for the Strategic Research Foundation at Private Universities, 2012–2016 (No. S1201020), Kaneka Corporation Award in Synthetic Organic Chemistry, Japan, JSPS KAKENHI Grant Numbers JP16H01161 in Middle Molecular Strategy and JP16K05781 in Scientific Research (C), a SUNBOR Grant from the Suntory Foundation for Life Sciences, and the Sasagawa Scientific Research Grant from the Japan Science Society.
PY - 2018
Y1 - 2018
N2 - Development of regio- and stereoselective glycosylations leading to a specific hydroxyl group among several free hydroxyl groups is a challenging and long-standing research subject in carbohydrate chemistry. In this context, several efficient regio- and stereoselective glycosylation methods utilizing organoboron reagents, which can bind reversibly to cis-1,2- or 1,3-diols under mild conditions, have been reported. In this focused review article, several organoboron-mediated regio- and stereoselective glycosylations are described, including recently developed methods.
AB - Development of regio- and stereoselective glycosylations leading to a specific hydroxyl group among several free hydroxyl groups is a challenging and long-standing research subject in carbohydrate chemistry. In this context, several efficient regio- and stereoselective glycosylation methods utilizing organoboron reagents, which can bind reversibly to cis-1,2- or 1,3-diols under mild conditions, have been reported. In this focused review article, several organoboron-mediated regio- and stereoselective glycosylations are described, including recently developed methods.
KW - Borinic acid
KW - Boronic acid
KW - Glycosylation
KW - Organoboron compound
KW - Regioselective
KW - Stereoselective
KW - Unprotected glycoside
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U2 - 10.4052/tigg.1817.2E
DO - 10.4052/tigg.1817.2E
M3 - Short survey
AN - SCOPUS:85047630949
VL - 30
SP - E55-E62
JO - Trends in Glycoscience and Glycotechnology
JF - Trends in Glycoscience and Glycotechnology
SN - 0915-7352
IS - 174
ER -