The regioselectivities observed in Baeyer-Villiger reaction of polyhydroxycyclohexanone derivatives possessing various substituents at adjacent carbons to the ketone carbonyl are reported. This study suggested that the trend of the migratory aptitude of substituted carbons would be a carbon with benzyloxy > methoxy > ketal oxygen ≫ acyloxy ∼ methyl.
|Number of pages||4|
|Publication status||Published - 1994 Sept 26|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry