Regulation of thermoresponsive properties and drug carrier application of nano-micelles via heterogeneous end-functional block copolymer blends

Masamichi Nakayama, Yayoi Kawahara, Hideko Kanazawa, Teruo Okano

Research output: Contribution to conferencePaper

Abstract

We prepared well-defined amphiphilic diblock copolymers comprising thermoresponsive segments and hydrophobic segments by reversible addition-fragmentation chain transfer radical polymerization. Terminal dithiobenzoate groups located at thermoresponsive chains were substituted with hydrophilic maleimede groups. Polymeric micelles were prepared by blend of heterogeneous end-functional diblock copolymers at any ratio in weight, and were characterized regading hydrodynamic diameters and thermoresponsive properties.

Original languageEnglish
Pages5455-5456
Number of pages2
Publication statusPublished - 2006 Dec 1
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: 2006 Sep 202006 Sep 22

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
CountryJapan
CityToyama
Period06/9/2006/9/22

Keywords

  • Drug carrier
  • Poly(N-isopropylacrylamide)
  • Polymer blend
  • Polymeric micelle
  • Reversible addition-fragmentation chain transfer radical polymerization
  • Thermoresponse

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Nakayama, M., Kawahara, Y., Kanazawa, H., & Okano, T. (2006). Regulation of thermoresponsive properties and drug carrier application of nano-micelles via heterogeneous end-functional block copolymer blends. 5455-5456. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.