Regulation of thermoresponsive properties and drug carrier application of nano-micelles via heterogeneous end-functional block copolymer blends

Masamichi Nakayama, Yayoi Kawahara, Hideko Kanazawa, Teruo Okano

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We prepared well-defined amphiphilic diblock copolymers comprising thermoresponsive segments and hydrophobic segments by reversible addition-fragmentation chain transfer radical polymerization. Terminal dithiobenzoate groups located at thermoresponsive chains were substituted with hydrophilic maleimede groups. Polymeric micelles were prepared by blend of heterogeneous end-functional diblock copolymers at any ratio in weight, and were characterized regading hydrodynamic diameters and thermoresponsive properties.

Original languageEnglish
Title of host publicationPolymer Preprints, Japan
Pages5455-5456
Number of pages2
Volume55
Edition2
Publication statusPublished - 2006
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: 2006 Sep 202006 Sep 22

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
CountryJapan
CityToyama
Period06/9/2006/9/22

Fingerprint

Micelles
Block copolymers
Free radical polymerization
Hydrodynamics

Keywords

  • Drug carrier
  • Poly(N-isopropylacrylamide)
  • Polymer blend
  • Polymeric micelle
  • Reversible addition-fragmentation chain transfer radical polymerization
  • Thermoresponse

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Nakayama, M., Kawahara, Y., Kanazawa, H., & Okano, T. (2006). Regulation of thermoresponsive properties and drug carrier application of nano-micelles via heterogeneous end-functional block copolymer blends. In Polymer Preprints, Japan (2 ed., Vol. 55, pp. 5455-5456)

Regulation of thermoresponsive properties and drug carrier application of nano-micelles via heterogeneous end-functional block copolymer blends. / Nakayama, Masamichi; Kawahara, Yayoi; Kanazawa, Hideko; Okano, Teruo.

Polymer Preprints, Japan. Vol. 55 2. ed. 2006. p. 5455-5456.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nakayama, M, Kawahara, Y, Kanazawa, H & Okano, T 2006, Regulation of thermoresponsive properties and drug carrier application of nano-micelles via heterogeneous end-functional block copolymer blends. in Polymer Preprints, Japan. 2 edn, vol. 55, pp. 5455-5456, 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan, 06/9/20.
Nakayama, Masamichi ; Kawahara, Yayoi ; Kanazawa, Hideko ; Okano, Teruo. / Regulation of thermoresponsive properties and drug carrier application of nano-micelles via heterogeneous end-functional block copolymer blends. Polymer Preprints, Japan. Vol. 55 2. ed. 2006. pp. 5455-5456
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